Document Detail


Polyester connecting ring improves outcome in nitinol composite artificial esophagus.
MedLine Citation:
PMID:  19730008     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In a previous study, we replaced a thoracic esophagus with nitinol composite artificial esophagus. Two major problems of anastomotic leakage and early sloughing of the grafted prostheses were noted. We have developed a new type of nitinol composite artificial esophagus with polyester connecting ring, and in this study, we test the effectiveness of replacing a thoracic esophagus with this new type of tube. We experimented with two groups: with polyester connecting ring (experimental) and without (control). The shedding time of artificial esophagus in the experimental group was significantly delayed compared with the control group (127.2 +/- 51.8 days vs. 27.6 +/- 15.7 days, respectively, p < 0.05). The incidence of the two major postoperative complications in the experimental group was significantly decreased compared with the control group: anastomotic leakage (0% vs. 33.3%, respectively, p < 0.05) and severe neoesophageal stenosis after prostheses sloughing (10% vs. 50%, respectively, p < 0.05). The long-term survival rate (>6 months) in the experimental group was significantly increased compared with the control group (100% vs. 10%, respectively, p < 0.05). These results suggest that the polyester connecting ring improves outcome of replacement of the thoracic esophagus with nitinol composite artificial esophagus.
Authors:
Jian-hui Liang; Xing Zhou; Zhao-bing Zheng; Xian-liang Liang
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  ASAIO journal (American Society for Artificial Internal Organs : 1992)     Volume:  55     ISSN:  1538-943X     ISO Abbreviation:  ASAIO J.     Publication Date:    2009 Sep-Oct
Date Detail:
Created Date:  2009-09-04     Completed Date:  2009-11-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204109     Medline TA:  ASAIO J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  514-8     Citation Subset:  IM    
Affiliation:
Department of Chest Surgery, the Second Affiliated Hospital of Guangzhou Medical College, Institute of Guangzhou Cardiovascular Diseases, Guangzhou, China. liangJH2006@163.com
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MeSH Terms
Descriptor/Qualifier:
Alloys*
Anastomosis, Surgical / instrumentation
Animals
Artificial Organs*
Esophagus / surgery*
Implants, Experimental / adverse effects
Polyesters*
Postoperative Complications / etiology
Swine
Chemical
Reg. No./Substance:
0/Alloys; 0/Polyesters; 52013-44-2/nitinol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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