| Polydrug use, cannabis, and psychosis-like symptoms. | |
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MedLine Citation:
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PMID: 18449850 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To examine psychosis-like symptoms in users of legal and illicit drugs. METHODS: Schizotypal Personality Questionnaire (SPQ) scores were compared in groups of people with different exposure to cannabis, with the use of other drugs serving as a covariate. Supplemental analyses compared users of legal and illicit drugs with cannabis use as a covariate. RESULTS: Weekly (n = 111) and monthly (n = 136) cannabis users had higher scores on the SPQ than former (n = 143) and non-users (n = 81). The use of other drugs accounted for the links between cannabis and schizotypy. Lifetime use of psychomotor stimulant drugs plus ecstasy accounted for associations between cannabis and scores on the SPQ and its different subscales. Dividing groups by type of drug use revealed that those who used only cannabis and legal drugs (CLDs) (n = 126) were no different from those who used only legal drugs (LDs) (n = 74) but both groups scored significantly lower on the SPQ than polydrug users (n = 247). When controlling for marijuana use in the last month, the significant difference across drug use groups remained. CONCLUSIONS: The results suggest that research on marijuana and schizotypy requires careful assessment of the use of other drugs, especially psychomotor stimulants and ecstasy. |
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Authors:
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Nicholas T Van Dam; Mitch Earleywine; Greg DiGiacomo |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Human psychopharmacology Volume: 23 ISSN: 1099-1077 ISO Abbreviation: Hum Psychopharmacol Publication Date: 2008 Aug |
Date Detail:
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Created Date: 2008-08-07 Completed Date: 2008-11-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8702539 Medline TA: Hum Psychopharmacol Country: England |
Other Details:
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Languages: eng Pagination: 475-85 Citation Subset: IM |
Copyright Information:
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(c) 2008 John Wiley & Sons, Ltd. |
Affiliation:
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Department of Psychology, University at Albany, SUNY, Albany, New York 12222, USA. nv122142@albany.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Central Nervous System Stimulants / adverse effects Cognition / drug effects Female Humans Male Marijuana Abuse / complications* N-Methyl-3,4-methylenedioxyamphetamine / adverse effects Psychoses, Substance-Induced / etiology* Questionnaires Schizotypal Personality Disorder / chemically induced* |
| Chemical | |
Reg. No./Substance:
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0/Central Nervous System Stimulants; 42542-10-9/N-Methyl-3,4-methylenedioxyamphetamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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