Document Detail

Polydioxanone absorbable sutures in vascular anastomoses: experimental and preliminary clinical studies.
MedLine Citation:
PMID:  7953459     Owner:  NLM     Status:  MEDLINE    
To assess the safety and efficacy of polydioxanone suture (PDS) for vascular anastomoses, bilateral carotid end-to-end anastomoses using PDSs on the left and Dacron sutures on the right in 18 dogs were performed. The anastomoses were assessed at 4, 6 and 8 weeks after surgery. A breaking-strength test (300 mmHg) did not show a significant difference between PDS and Dacron anastomoses, but partial absorption was grossly evident in the PDS group. Some 35 venous and 21 arterial reconstructive procedures were also carried out using PDS in 53 patients. At follow-up of 3-5 (mean 3.5) years, none of the patients had experienced any suture-related complications. The results indicate that PDS maintains an adequate tensile strength in anastomoses until suture-line healing occurs, suggesting that this material may be safely used in venous or small arterial anastomoses. In addition, because it is absorbable, resulting in decreased foreign-body reactions, PDS may have the potential to improve the long-term patency of venous or small arterial reconstructions.
Z G Wang; L Q Pu; G D Li; W Du; J F Symes
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article    
Journal Detail:
Title:  Cardiovascular surgery (London, England)     Volume:  2     ISSN:  0967-2109     ISO Abbreviation:  Cardiovasc Surg     Publication Date:  1994 Aug 
Date Detail:
Created Date:  1994-11-30     Completed Date:  1994-11-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9308765     Medline TA:  Cardiovasc Surg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  508-13     Citation Subset:  IM    
Vascular Institute, Beijing Post and Telecom Hospital, China.
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MeSH Terms
Anastomosis, Surgical / instrumentation*
Middle Aged
Polyethylene Terephthalates
Vascular Surgical Procedures / instrumentation*
Reg. No./Substance:
0/Polyethylene Terephthalates; 31621-87-1/Polydioxanone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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