Document Detail


[Polycythemia].
MedLine Citation:
PMID:  21064012     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Polycythemia is defined by the increase of hematocrit and haemoglobin respectively. Possible causes might be neoplastic diseases like polycythemia vera with proliferation of a cell clone. More often one will find reactive forms resulting from chronic hypoxemia. A physiologic form of polycythemia can be found in highlanders and athletes training at high altitude. With increasing frequency erytrhopoetin and it's analoga are being used as doping substances to induce Polycythemia. Red cell proliferation induced by chronic hypoxemia is the most common form in patients. In this instance the lung itself can be the cause (hypoxemia with hypocapnea in blood gas analysis) or hypoventilation caused by an insufficient respiratory pump (hypercapnea with hypoxemia in blood gas analysis) induces a compensatory Polycythemia. The former form can be treated with long term oxygen therapy and the latter by non-invasive ventilation, either approach corrects hypoxemia and reduces Polycythemia within some weeks.
Authors:
D Köhler; D Dellweg
Publication Detail:
Type:  English Abstract; Journal Article; Review     Date:  2010-11-09
Journal Detail:
Title:  Deutsche medizinische Wochenschrift (1946)     Volume:  135     ISSN:  1439-4413     ISO Abbreviation:  Dtsch. Med. Wochenschr.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-10     Completed Date:  2010-12-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0006723     Medline TA:  Dtsch Med Wochenschr     Country:  Germany    
Other Details:
Languages:  ger     Pagination:  2300-3     Citation Subset:  IM    
Copyright Information:
© Georg Thieme Verlag KG Stuttgart · New York.
Affiliation:
Fachkrankenhaus Kloster Grafschaft, Schmallenberg. d.koehler@fkkg.de
Vernacular Title:
Polyglobulie.
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MeSH Terms
Descriptor/Qualifier:
Altitude
Animals
Anoxia / complications,  therapy
Humans
Mammals / blood
Neoplasms / complications
Oxygen Inhalation Therapy
Polycythemia* / blood,  etiology,  therapy

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