| Polycystic ovary syndrome: symptomatology, pathophysiology, and epidemiology. | |
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MedLine Citation:
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PMID: 9855614 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Women with polycystic ovary syndrome seek health care for 3 major reasons: infertility, menstrual irregularity, and androgen excess. The infertility is associated with anovulation. The menstrual irregularity is typically chronic, beginning with menarche. Although amenorrhea may sometimes occur, the more common presentation is irregular bleeding characteristic of anovulation. Androgen excess may be manifested by varying degrees of hirsutism. Patients may also report acne. The rapid development of virilizing signs, such as deepening of the voice, increased muscle mass, and temporal balding, should prompt a search for a tumor and lead one away from a diagnosis of polycystic ovary syndrome. Typically treatment is directed at alleviating the symptoms: ovulation induction for infertility, oral contraceptives or a progestin for menstrual irregularity, and oral contraceptives or spironolactone for hirsutism. On the basis of recent epidemiologic data suggestive of increased cardiovascular risk among women with polycystic ovary syndrome, such treatment might be complemented by a long-term approach that addresses the underlying pathophysiology of insulin resistance. |
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Authors:
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D Guzick |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 179 ISSN: 0002-9378 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 1998 Dec |
Date Detail:
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Created Date: 1999-01-14 Completed Date: 1999-01-14 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: S89-S93 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics and Gynecology, University of Rochester, Rochester, New York, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Androgens
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blood Female Gonadotropins / physiology Humans Insulin Resistance / physiology Polycystic Ovary Syndrome* / complications, epidemiology, physiopathology Prevalence Risk Factors |
| Chemical | |
Reg. No./Substance:
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0/Androgens; 0/Gonadotropins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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