| Polycystic ovary syndrome: dynamic contrast-enhanced ovary MR imaging. | |
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MedLine Citation:
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PMID: 15186884 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: to determine the enhancement behaviour of the ovaries in women with polycystic ovary syndrome (PCOS) by dynamic contrast-enhanced magnetic resonance (DCE-MR) imaging and to compare these data with those of normal ovulating controls. METHOD: 24 women with PCOS and 12 controls underwent DCE-MR imaging. Dynamic images were acquired before and after injection of a contrast bolus at 30 s and the min of 1, 2, 3, 4 and 5. On postprocessing examination: (i) the ovarian volumes; (ii) the signal intensity value of each ovary per dynamic study; (iii) early-phase enhancement rate; (iv) time to peak enhancement (T(p)); and (v) percentage of washout of 5th min were determined. Data of the ovaries of the women with PCOS and controls were compared with Mann-Whitney U-test. RESULTS: the mean values of T(p) were found to be significantly lower in women with PCOS than in controls (p < 0.05). On the other hand, the mean values of ovarian volume, the early-phase enhancement rate, and percentage of washout of 5th min of ovaries were significantly higher in PCOS patients (p < 0.05). Examination of the mean signal intensity-time curve revealed the ovaries in women with PCOS showed a faster and greater enhancement and wash-out. CONCLUSION: the enhancement behaviour of ovaries of women with PCOS may be significantly different from those of control subjects on DCE-MR imaging examination. In our experience, it is a valuable modality to highlight the vascularization changes in ovarian stroma with PCOS. We believe that improved DCE-MR imaging techniques may also provide us additional parameters in the diagnosis and treatment strategies of PCOS. |
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Authors:
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C Zuhal Erdem; Ulku Bayar; L Oktay Erdem; Aykut Barut; Sadi Gundogdu; Erdal Kaya |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: European journal of radiology Volume: 51 ISSN: 0720-048X ISO Abbreviation: Eur J Radiol Publication Date: 2004 Jul |
Date Detail:
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Created Date: 2004-06-09 Completed Date: 2005-03-10 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8106411 Medline TA: Eur J Radiol Country: Ireland |
Other Details:
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Languages: eng Pagination: 48-53 Citation Subset: IM |
Affiliation:
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Department of Radiology, Zonguldak Karaelmas University, School of Medicine, 67600 Kozlu, Zonguldak, Turkey. sunarerdem@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Contrast Media Female Gadolinium DTPA / diagnostic use Humans Magnetic Resonance Imaging / methods* Polycystic Ovary Syndrome / pathology* Prospective Studies Statistics, Nonparametric |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 80529-93-7/Gadolinium DTPA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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