Document Detail


Polycystic ovary syndrome and autoimmunity.
MedLine Citation:
PMID:  20816585     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Polycystic ovary syndrome (PCOS) is characterized by laboratory and/or clinical features consisting of hyperandrogenism with chronic anovulation and is currently one of the most common endocrinopathies in women of fertile age. PCOS is associated with a variety of endocrine and metabolic disturbances. It was demonstrated that the prevalence of autoimmune thyroiditis is high among these patients. Recent studies reveal a higher incidence of autoantibodies such as anti-histone, anti-dsDNA presented in systemic autoimmune disease, however their clinical significance is still unknown. According to results of current research the syndrome could be possibly associated with some autoimmune diseases. Further studies are required to determine the role of organ-specific and non-specific autoantibodies in patients with PCOS.
Authors:
Jana Petríková; Ivica Lazúrová; Shoenfeld Yehuda
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Publication Detail:
Type:  Journal Article; Review     Date:  2010-07-24
Journal Detail:
Title:  European journal of internal medicine     Volume:  21     ISSN:  1879-0828     ISO Abbreviation:  Eur. J. Intern. Med.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-06     Completed Date:  2010-12-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9003220     Medline TA:  Eur J Intern Med     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  369-71     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2010. Published by Elsevier B.V.
Affiliation:
1st Department of Internal Medicine, University Hospital, Safarikiensis University, Kosice, Slovakia.
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MeSH Terms
Descriptor/Qualifier:
Autoantibodies / blood
Autoimmune Diseases / immunology*
Autoimmunity / immunology*
Female
Humans
Hyperandrogenism / immunology*
Polycystic Ovary Syndrome / immunology*
Chemical
Reg. No./Substance:
0/Autoantibodies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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