| Polycystic ovary syndrome: an ancient disorder? | |
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MedLine Citation:
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PMID: 20979996 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Polycystic ovary syndrome (PCOS) appears to be an ancient disorder, which has persisted in human evolution despite reduced fecundity because of the benefits to affected women such as greater sturdiness and improved energy utilization, a rearing advantage for their children and kin, and a reduction in the risk of perinatal mortality. This raises the possibility that gene variants that are eventually found to be associated with PCOS will be similar across ethnic groups and races. |
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Authors:
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Ricardo Azziz; Daniel A Dumesic; Mark O Goodarzi |
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Publication Detail:
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Type: Historical Article; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review Date: 2010-10-27 |
Journal Detail:
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Title: Fertility and sterility Volume: 95 ISSN: 1556-5653 ISO Abbreviation: Fertil. Steril. Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-03-22 Completed Date: 2011-05-11 Revised Date: 2012-04-04 |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: United States |
Other Details:
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Languages: eng Pagination: 1544-8 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, California, USA. razziz@mcg.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Continental Population Groups
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genetics Female Genetic Predisposition to Disease / ethnology History of Medicine* History, Ancient History, Medieval Humans Linkage Disequilibrium Obesity / complications, epidemiology, ethnology Polycystic Ovary Syndrome* / epidemiology, ethnology, etiology, genetics Prevalence Risk Factors |
| Grant Support | |
ID/Acronym/Agency:
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R01 DK073632-06/DK/NIDDK NIH HHS; R01 HD029364-14/HD/NICHD NIH HHS; R01 HD029364-15/HD/NICHD NIH HHS; R01-DK79888/DK/NIDDK NIH HHS; R01-HD29364/HD/NICHD NIH HHS |
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