Document Detail

Polycyclic aromatic hydrocarbons, carbon monoxide, "tar", and nicotine in the mainstream smoke aerosol of the narghile water pipe.
MedLine Citation:
PMID:  15778004     Owner:  NLM     Status:  MEDLINE    
A smoking machine protocol and yields for "tar", nicotine, PAH, and CO are presented for the standard 171-puff steady periodic smoking regimen proposed by Shihadeh et al. [Shihadeh, A., Azar, S., Antonios, C., Haddad, A., 2004b. Towards a topographical model of narghile water-pipe cafe smoking: A pilot study in a high socioeconomic status neighborhood of Beirut, Lebanon. Pharmacology Biochemistry and Behavior 79(1), 75]. Results show that smokers are likely exposed to more "tar" and nicotine than previously thought, and that pyronsynthesized PAH are present in the "tar" despite the low temperatures characteristic of the tobacco in narghile smoking. With a smoking regimen consisting of 171 puffs each of 0.53l volume and 2.6s duration with a 17 s interpuff interval, the following results were obtained for a single smoking session of 10 g of mo'assel tobacco paste with 1.5 quick-lighting charcoal disks applied to the narghile head: 2.94 mg nicotine, 802 mg "tar", 145 mg CO, and relative to the smoke of a single cigarette, greater quantities of chrysene, phenanthrene, and fluoranthene. Anthracene and pyrene were also identified but not quantified. The results indicate that narghile smoke likely contains an abundance of several of the chemicals thought to be causal factors in the elevated incidence of cancer, cardiovascular disease and addiction in cigarette smokers.
Alan Shihadeh; Rawad Saleh
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association     Volume:  43     ISSN:  0278-6915     ISO Abbreviation:  Food Chem. Toxicol.     Publication Date:  2005 May 
Date Detail:
Created Date:  2005-03-21     Completed Date:  2005-04-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8207483     Medline TA:  Food Chem Toxicol     Country:  England    
Other Details:
Languages:  eng     Pagination:  655-61     Citation Subset:  IM    
Aerosol Research Laboratory, Department of Mechanical Engineering, American University of Beirut, PO Box 11-0236, Riad El Solh, Beirut, Lebanon.
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MeSH Terms
Carbon Monoxide / analysis*
Carcinogens / analysis*
Chrysenes / analysis
Enzyme Inhibitors / analysis
Filtration / instrumentation
Fluorenes / analysis
Nicotine / analysis*
Phenanthrenes / analysis
Plants, Toxic
Polycyclic Hydrocarbons, Aromatic / analysis*
Smoke / analysis*
Smoking / adverse effects
Tars / analysis,  chemistry*
Tobacco / chemistry*
Tobacco Smoke Pollution / analysis
Reg. No./Substance:
0/Aerosols; 0/Carcinogens; 0/Chrysenes; 0/Enzyme Inhibitors; 0/Fluorenes; 0/Phenanthrenes; 0/Polycyclic Hydrocarbons, Aromatic; 0/Smoke; 0/Tars; 0/Tobacco Smoke Pollution; 0/tobacco tar; 206-44-0/fluoranthene; 218-01-9/chrysene; 54-11-5/Nicotine; 630-08-0/Carbon Monoxide; 85-01-8/phenanthrene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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