| Polyclonal plasma cell proliferation with marked hypergammaglobulinemia and multiple autoantibodies. | |
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MedLine Citation:
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PMID: 17127739 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 77-yr-old man presented with marked peripheral blood and bone marrow plasmacytosis, marked hypergammaglobulinemia, and multiple autoantibodies. Serum protein immunofixation and immunophenotyping of bone marrow plasma cells by flow cytometry and immunohistochemistry disclosed polyclonal proliferation of plasma cells at various stages of differentiation. The presence of multiple autoantibodies in the patient's serum suggests that an autoimmune disease underlies the polyclonal proliferation of plasma cells. |
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Authors:
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Lin Li; Peihong Hsu; Keyur Patel; Yasi Saffari; Ida Ashley; Judith Brody |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Annals of clinical and laboratory science Volume: 36 ISSN: 0091-7370 ISO Abbreviation: Ann. Clin. Lab. Sci. Publication Date: 2006 |
Date Detail:
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Created Date: 2006-11-27 Completed Date: 2007-01-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0410247 Medline TA: Ann Clin Lab Sci Country: United States |
Other Details:
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Languages: eng Pagination: 479-84 Citation Subset: IM |
Affiliation:
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Department of Pathology & Laboratory Medicine, North Shore University Hospital, Manhasset, NY 11030, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Antigens, CD / metabolism Autoantibodies / immunology* Bone Marrow / pathology* Cell Proliferation Clone Cells Flow Cytometry Humans Hypergammaglobulinemia / immunology*, metabolism, pathology* Immunophenotyping Male Plasma Cells / immunology*, metabolism, pathology* |
| Chemical | |
Reg. No./Substance:
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0/Antigens, CD; 0/Autoantibodies |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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