Document Detail


Polychlorinated naphthalenes in animal aquatic species and human exposure through the diet: a review.
MedLine Citation:
PMID:  15553160     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Polychlorinated naphthalenes (PCNs) are a group of environmental pollutants, which contain one to eight chlorine atoms per naphthalene molecule, forming a total of 75 possible congeners. Several of the PCN congeners display toxicity similar to that of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) through AhR-mediated mechanisms. There are toxicological similarities between PCNs and other well known environmental contaminants such as polychlorinated dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs) and biphenyls (PCBs). However, in contrast to these compounds, information on exposure to PCNs for non-occupationally exposed populations is rather scarce. In this article, information on human exposure to PCNs through dietary intake is reviewed. Because this information is very limited and taking into account that most data on PCN levels in potential foods concern to aquatic species, these data are also reviewed. It is concluded that further investigations on dietary intake and potential human health effects of PCNs are clearly necessary.
Authors:
José L Domingo
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of chromatography. A     Volume:  1054     ISSN:  0021-9673     ISO Abbreviation:  J Chromatogr A     Publication Date:  2004 Oct 
Date Detail:
Created Date:  2004-11-19     Completed Date:  2005-03-07     Revised Date:  2009-01-15    
Medline Journal Info:
Nlm Unique ID:  9318488     Medline TA:  J Chromatogr A     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  327-34     Citation Subset:  IM    
Affiliation:
Laboratory of Toxicology and Environmental Health, School of Medicine, Rovira i Virgili University, San Lorenzo 21, Reus 43201, Spain. jlldr@fmcs.urv.es
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MeSH Terms
Descriptor/Qualifier:
Animals
Diet*
Food Chain*
Humans
Hydrocarbons, Chlorinated / administration & dosage,  analysis*,  toxicity
Naphthalenes / administration & dosage,  analysis*,  toxicity
Chemical
Reg. No./Substance:
0/Hydrocarbons, Chlorinated; 0/Naphthalenes

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