Document Detail

Polychlorinated biphenyls: persistent pollutants with immunological, neurological, and endocrinological consequences.
MedLine Citation:
PMID:  21438643     Owner:  NLM     Status:  In-Data-Review    
Polychlorinated biphenyls (PCBs) are considered "persistent organic pollutants;" fat-soluble compounds that bioaccumulate in individuals and biomagnify in the food chain. PCBs were the first industrial compounds to experience a worldwide ban on production because of their potent toxicity. These compounds are still present in our food supply (fish, dairy, hamburger, and poultry being the most contaminated) and our bodies. Once in the body, they can cause long-term problems, especially for those exposed in utero. PCB bioaccumulation can lead to reduced infection fighting ability, increased rates of autoimmunity, cognitive and behavioral problems, and hypothyroidism. Some research also links PCBs to increased rates of type 2 diabetes. Testing is currently available for some of the most damaging PCBs. The testing compares individual levels to national reference values and can be interpreted to determine current exposure. Dietary measures can be enacted that will reduce PCB half-lives in humans by increasing excretion.
Walter J Crinnion
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Alternative medicine review : a journal of clinical therapeutic     Volume:  16     ISSN:  1089-5159     ISO Abbreviation:  Altern Med Rev     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-03-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9705340     Medline TA:  Altern Med Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  5-13     Citation Subset:  K    
Professor and chair of the Environmental Medicine Program, Southwest College of Naturopathic Medicine, Tempe, AZ; Environmental Medicine Editor, Alternative Medicine Review; Email:
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