Document Detail


Polybrominated diphenyl ethers and synthetic musks in umbilical cord serum, maternal serum, and breast milk from Seoul, South Korea.
MedLine Citation:
PMID:  20444483     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fetal and maternal exposure levels of two emerging pollutants, polybrominated diephenyl ethers (PBDEs) and synthetic musks, were measured in Korean general population to assess prenatal and postnatal exposures in infants. For this purpose, paired samples of breast milk, maternal and cord blood were collected from 20 Korean women in 2007. In comparison to data from other countries and previous data from Korea, relatively higher and gradually increasing concentrations for PBDEs were found in Korean breast milk (< LOQ to 590 ng g(-1) lipid wt; median=90 ng g(-1)). Differences in PBDEs and musk concentrations were found among age groups and parity levels. PBDEs concentrations in breast milk were lower in the younger mothers and/or the mothers with multiple parities, while these trends were not found for musks. Compared with PBDEs, concentrations of musks were significantly lower in breast milk than in serum and a little correlation in concentrations among the three human biological matrices were observed. The differences in the profiles of musks relative to PBDEs were due to different clearance rates between these two compounds. The average hazard quotients (HQs) for daily intake of PBDEs by infants via lactation were 0.62, 0.42, and 0.19 for BDE-47, BDE-99, and BDE-153, respectively.
Authors:
Chang Seong Kang; Jong-Hyeon Lee; Seung-Kyu Kim; Kyu-Tae Lee; Jung Suk Lee; Pan Soo Park; Se Hun Yun; Kurunthachalam Kannan; Yung Wook Yoo; Jeong Yi Ha; Seung Wook Lee
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-05-04
Journal Detail:
Title:  Chemosphere     Volume:  80     ISSN:  1879-1298     ISO Abbreviation:  Chemosphere     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-20     Completed Date:  2010-08-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0320657     Medline TA:  Chemosphere     Country:  England    
Other Details:
Languages:  eng     Pagination:  116-22     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2010 Elsevier Ltd. All rights reserved.
Affiliation:
Department of OB&GYN, KEPCO Medical Foundation, Hanil General Hospital, Seoul, Republic of Korea.
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MeSH Terms
Descriptor/Qualifier:
Adult
Environmental Monitoring
Environmental Pollutants / blood,  metabolism*
Female
Fetal Blood / metabolism*
Halogenated Diphenyl Ethers / blood,  metabolism*
Humans
Maternal Exposure
Milk, Human / metabolism*
Perfume / metabolism*
Republic of Korea
Chemical
Reg. No./Substance:
0/Environmental Pollutants; 0/Halogenated Diphenyl Ethers; 0/Perfume

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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