Document Detail

Polybrominated diphenyl ethers and hydroxylated and methoxylated brominated and chlorinated analogues in the plasma of fish from the Detroit River.
MedLine Citation:
PMID:  16124294     Owner:  NLM     Status:  MEDLINE    
Novel classes and congeners of contaminant residues that are structurally analogous to polybrominated diphenyl ether (PBDE) flame retardants were assessed in the plasma of seven benthic- and six pelagic-feeding fish species from the highly contaminated Detroit River corridor, namely, hydroxylated-PBDEs (OH-PBDEs), methoxylated-PBDEs (MeO-PBDEs), and the antimicrobial OH-trichlorodiphenyl ether, triclosan, and its methylated (MeO) triclosan analogue. In all samples sigmaPBDE concentrations were comprised mainly of BDE47, BDE99, and BDE100 (>85%) and ranged from 155 pg/g wet weight (ww) to 21 069 pg/g ww. Of the 14 OH-PBDE congeners assessed, as many as 10 congeners were identified, although profiles were generally dominated by 6-OH-BDE47 with lesser amounts of 2'-OH-BDE68, 4'-OH-BDE49, and 4-OH-BDE42. sigmaOH-PBDE concentrations ranged from 2.7 to 198 pg/g ww, with sigmaPBDE to sigmaOH-PBDE concentration ratios ranging from 0.0005 to 0.02. OH-PBDEs are likely derived in these freshwater species as metabolites of precursor PBDEs and are subsequently retained in the blood, for example, 6-OH-BDE47, 4'-OH-BDE49, and 4-OH-BDE42 could be derived from BDE47. Portions of concentrations of the OH-PBDEs may also be of alternate origins and are accumulated and retained in these fish. In all samples, the 14 MeO-PBDEs monitored were below detection (<0.01 pg/g ww). Anthropogenic triclosan concentrations ranged from 750 to >10 000 pg/g ww and is clearly a bioaccumulative halogenated phenolic compound in these fish. MeO-triclosan concentrations were considerably lower. In addition to emerging classes of brominated contaminant such as PBDEs, whether of metabolic or anthropogenic origin, fish collected from the Detroit River are exposed to a complex profile of PBDE-like organohalogens.
Karlis Valters; Hongxia Li; Mehran Alaee; Ivy D'Sa; Göran Marsh; Ake Bergman; Robert J Letcher
Related Documents :
7736374 - Toxins and tradition: the impact of food-chain contamination on the inuit of northern q...
10739044 - Results of an "emergency quality control study" as confirmation of a pcdd/pcdf-contamin...
23737564 - Long-day photoperiod interacts with vasopressin and food restriction to modulate reprod...
16844194 - Influence of temperature on pcdd/pcdf desorption from waste incineration flyash under n...
6852884 - Effects of dynamic and static body weight loss on taste responses.
6381014 - Food interactions affecting the absorption of analgesic and anti-inflammatory agents.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Environmental science & technology     Volume:  39     ISSN:  0013-936X     ISO Abbreviation:  Environ. Sci. Technol.     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-08-29     Completed Date:  2005-11-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0213155     Medline TA:  Environ Sci Technol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  5612-9     Citation Subset:  IM    
Great Lakes Institute for Environmental Research, University of Windsor, Windsor, Ontario, N9B 3P4 Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Environmental Monitoring
Fishes / blood*
Phenyl Ethers / blood*,  chemistry
Polybrominated Biphenyls / blood*,  chemistry
Polychlorinated Biphenyls / blood*,  chemistry
Water Pollutants, Chemical / blood*
Reg. No./Substance:
0/Phenyl Ethers; 0/Polybrominated Biphenyls; 0/Polychlorinated Biphenyls; 0/Water Pollutants, Chemical

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Polychlorinated dioxins, furans, and biphenyls, and polybrominated diphenyl ethers in a U.S. meat ma...
Next Document:  Evidence for biogenic pyromorphite formation by the nematode Caenorhabditis elegans.