Document Detail

Polyarthritis associated with visceral leishmaniasis in a juvenile dog.
MedLine Citation:
PMID:  16824686     Owner:  NLM     Status:  MEDLINE    
Canine visceral leishmaniasis (CL) is a zoonosis and a chronic systemic disease characterized by a wide spectrum of clinical signs, including, in rare occasions, polyarthritis. This report describes a case of CL in an 8-month old male boxer dog with a history of lameness, fever and lymphadenopathy. A definitive diagnosis of CL was based on the observation of the Leishmania amastigotes seen concomitantly, and for the first time, in the lymph nodes aspiration smears (in macrophages), synovial fluid (in macrophages and neutrophils) and blood (in neutrophils). Despite this extensive dissemination of the parasite, the animal was successfully treated with a multi-step combination of meglumine antimoniate, aminosidine and allopurinol.
Marta Santos; Ricardo Marcos; Mónica Assunção; Augusto J F Matos
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2006-07-05
Journal Detail:
Title:  Veterinary parasitology     Volume:  141     ISSN:  0304-4017     ISO Abbreviation:  Vet. Parasitol.     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2006-10-18     Completed Date:  2006-12-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7602745     Medline TA:  Vet Parasitol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  340-4     Citation Subset:  IM    
Cytology Diagnostic Services, Laboratory of Histology and Embryology, ICBAS - Institute of Biomedical Sciences Abel Salazar, Porto, Portugal.
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MeSH Terms
Antiprotozoal Agents / therapeutic use*
Arthritis / blood,  drug therapy,  etiology,  veterinary*
Dog Diseases / blood,  drug therapy,  parasitology*
Drug Therapy, Combination
Leishmaniasis, Visceral / blood,  complications,  drug therapy,  veterinary*
Treatment Outcome
Reg. No./Substance:
0/Antiprotozoal Agents

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