Document Detail


Polyarteritis nodosa with pulmonary vasculitis.
MedLine Citation:
PMID:  8542157     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Although early postmortem series reported pulmonary involvement as a relatively common manifestation of polyarteritis nodosa (PAN), using the modern classification of PAN pulmonary involvement is very uncommon. A 62-yr-old male with well-documented classic PAN was found to have an arteritis of medium-sized muscular pulmonary arteries. The patient subsequently demonstrated a complete response to treatment. Of the few reported cases of PAN with pulmonary manifestations, the majority are autopsy series and the vascular lesion involves the bronchial arteries. There are no case reports of patients with pulmonary involvement of PAN who responded successfully to treatment. This case is the first description of a premortum diagnosis of pulmonary arteritis in PAN in which the patient had a response to treatment.
Authors:
J Nick; R Tuder; R May; J Fisher
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of respiratory and critical care medicine     Volume:  153     ISSN:  1073-449X     ISO Abbreviation:  Am. J. Respir. Crit. Care Med.     Publication Date:  1996 Jan 
Date Detail:
Created Date:  1996-02-13     Completed Date:  1996-02-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9421642     Medline TA:  Am J Respir Crit Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  450-3     Citation Subset:  AIM; IM    
Affiliation:
Division of Pulmonary Sciences, University of Colorado Health Sciences Center, Denver 80262, USA.
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MeSH Terms
Descriptor/Qualifier:
Alkylating Agents / administration & dosage,  therapeutic use
Anti-Inflammatory Agents / administration & dosage,  therapeutic use
Biopsy
Cyclophosphamide / administration & dosage,  therapeutic use
Follow-Up Studies
Humans
Male
Middle Aged
Polyarteritis Nodosa* / drug therapy,  pathology
Prednisone / administration & dosage,  therapeutic use
Pulmonary Artery* / pathology
Time Factors
Chemical
Reg. No./Substance:
0/Alkylating Agents; 0/Anti-Inflammatory Agents; 50-18-0/Cyclophosphamide; 53-03-2/Prednisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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