Document Detail

Polyamines in human breast milk for preterm and term infants.
MedLine Citation:
PMID:  23286699     Owner:  NLM     Status:  Publisher    
Maternal milk is the first source of exogenous polyamines for the newborn. Polyamines modulate gut maturation in neonates, but no studies are available on polyamine concentration in human milk of preterm babies, even though they could be important for their immature gut. The present study aimed to determine polyamine concentration in human breast milk of mothers with preterm or term infants during the first month of lactation. Human milk samples were obtained during the first month of lactation from twenty-seven mothers with preterm babies and twelve mothers with babies born at term. The polyamine concentration in human milk was quantified by HPLC. During the first month of lactation, the total polyamine concentration was significantly higher in preterm milk than in term milk samples (7590 (sd 4990) v. 4660 (sd 4830) nmol/l, respectively (P = 0·034)), as well as individual polyamine concentrations. Polyamine concentration in mature milk for preterm babies was significantly higher than that in mature milk for babies at term, and a similar trend was observed in colostrum and transition human milk. The spermidine/spermine ratio was higher in transition milk in preterm v. term samples, while in mature milk, the ratio was significantly lower in preterm than in term babies. In conclusion, the polyamine concentration was significantly higher in human milk for preterm than for term infants. This and the different spermidine/spermine ratios could influence the gut development of premature babies.
J Plaza-Zamora; M Sabater-Molina; M Rodríguez-Palmero; M Rivero; V Bosch; J M Nadal; S Zamora; E Larqué
Related Documents :
23834679 - Bronchopulmonary dysplasia in preterm infants managed with non-invasive ventilation or ...
2795349 - Quantitation of urinary carnitine esters in a patient with medium-chain acyl-coenzyme a...
24576499 - Blood biochemical profile of very preterm infants before and after trophic feeding with...
10517369 - Urine screening of five-day-old newborns: metabolic profiling of neonatal galactosuria.
1497999 - A reappraisal of the measurement of glomerular filtration rate in pre-term infants.
20856169 - Arginine is synthesized from proline, not glutamate, in enterally fed human preterm neo...
7300289 - Analysis of the sibship patterns of stutterers.
7981479 - The role of mother's voice in the organization of brain function in the newborn.
20731829 - Neurodevelopmental toxicity of prenatal polychlorinated biphenyls (pcbs) by chemical st...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-3
Journal Detail:
Title:  The British journal of nutrition     Volume:  -     ISSN:  1475-2662     ISO Abbreviation:  Br. J. Nutr.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372547     Medline TA:  Br J Nutr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-5     Citation Subset:  -    
Department of Physiology, Faculty of Biology, Campus Mare Nostrum, University of Murcia, 30100, Murcia, Spain.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Characterization of electroencephalographic and biochemical responses at 5-HT promoting drug-induced...
Next Document:  3-D solar cells by electrochemical-deposited Se layer as extremely-thin absorber and hole conducting...