| Poly-lactic acid synthesis for application in biomedical devices - A review. | |
| | |
MedLine Citation:
|
PMID: 21756992 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Bioabsorbable polymers are considered a suitable alternative to the improvement and development of numerous applications in medicine. Poly-lactic acid (PLA,) is one of the most promising biopolymers due to the fact that the monomers may produced from non toxic renewable feedstock as well as is naturally occurring organic acid. Lactic acid can be made by fermentation of sugars obtained from renewable resources as such sugarcane. Therefore, PLA is an eco-friendly product with better features for use in the human body (nontoxicity). Lactic acid polymers can be synthesized by different processes so as to obtain products with an ample variety of chemical and mechanical properties. Due to their excellent biocompatibility and mechanical properties, PLA and their copolymers are becoming widely used in tissue engineering for function restoration of impaired tissues. In order to maximize the benefits of its use, it is necessary to understand the relationship between PLA material properties, the manufacturing process and the final product with desired characteristics. In this paper, the lactic acid production by fermentation and the polymer synthesis such biomaterial are reviewed. The paper intends to contribute to the critical knowledge and development of suitable use of PLA for biomedical applications. |
| | |
Authors:
|
Astrid J R Lasprilla; Guillermo A R Martinez; Betânia H Lunelli; André L Jardini; Rubens Maciel Filho |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-7-6 |
Journal Detail:
|
Title: Biotechnology advances Volume: - ISSN: 1873-1899 ISO Abbreviation: - Publication Date: 2011 Jul |
Date Detail:
|
Created Date: 2011-7-15 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8403708 Medline TA: Biotechnol Adv Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
|
Laboratory of Optimization, Design and Advanced Control, School of Chemical Engineering, State University of Campinas, Campinas (SP), Brazil; Institute of Biofabrication, Campinas (SP), Brazil. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Microbial production of polyhydroxybutyrate with tailor-made properties: An integrated modelling app...
Next Document: Cellular response to the deposition of diesel exhaust particle aerosols onto human lung cells grown ...