Document Detail


Poliomyelitis: 20 years--the Pondicherry experience.
MedLine Citation:
PMID:  2558226     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
During a 20-year period, 12,830 cases of acute poliomyelitis in children (aged 1 month-12 years) were seen in a South Indian teaching hospital (Pondicherry). Almost three-quarters (72.4%) of children were below the age of 2 years. The median age at onset of poliomyelitis shifted from 19.5 months (in the period 1968-1977) to 11 months (in the years 1978-1987). After 1981, epidemic peaks were noted every third year. 66.3% of cases had not received even a single dose of oral polio vaccine and 14.7% cases were vaccine failures (in the years 1983-1987). Provocation of poliomyelitis occurred in 66% of children and usually followed intragluteal injections associated with treatment of non-specific fevers. The overall mortality was 2.13%, the major cause of death being respiratory failure (60%). Polio virus type 1 was the major isolate among selected cases studied during 1983-1987. The risk factors identified in our study are lack of immunization and administration of intramuscular injections during the pre-paralytic phase. Ensuring early administration of multiple doses of oral polio vaccine to infants and avoiding intramuscular injections in young febrile children are important measures for the control of poliomyelitis--a continuing problem in Southern India.
Authors:
S Mahadevan; S Ananthakrishnan; S Srinivasan; P Nalini; R K Puri; S Badrinath; R S Rao
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of tropical medicine and hygiene     Volume:  92     ISSN:  0022-5304     ISO Abbreviation:  J Trop Med Hyg     Publication Date:  1989 Dec 
Date Detail:
Created Date:  1990-02-15     Completed Date:  1990-02-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0406044     Medline TA:  J Trop Med Hyg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  416-21     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Fawaharlal Institute of Post-Graduate Medical Education and Research, Pondicherry, India.
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MeSH Terms
Descriptor/Qualifier:
Age Factors
Child, Preschool
Disease Outbreaks*
Female
Humans
Immunization
India / epidemiology
Infant
Male
Poliomyelitis / epidemiology*,  mortality
Poliovirus / isolation & purification
Poliovirus Vaccine, Oral / administration & dosage*
Risk Factors
Seasons
Sex Factors
Chemical
Reg. No./Substance:
0/Poliovirus Vaccine, Oral

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