| Poliomyelitis: 20 years--the Pondicherry experience. | |
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MedLine Citation:
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PMID: 2558226 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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During a 20-year period, 12,830 cases of acute poliomyelitis in children (aged 1 month-12 years) were seen in a South Indian teaching hospital (Pondicherry). Almost three-quarters (72.4%) of children were below the age of 2 years. The median age at onset of poliomyelitis shifted from 19.5 months (in the period 1968-1977) to 11 months (in the years 1978-1987). After 1981, epidemic peaks were noted every third year. 66.3% of cases had not received even a single dose of oral polio vaccine and 14.7% cases were vaccine failures (in the years 1983-1987). Provocation of poliomyelitis occurred in 66% of children and usually followed intragluteal injections associated with treatment of non-specific fevers. The overall mortality was 2.13%, the major cause of death being respiratory failure (60%). Polio virus type 1 was the major isolate among selected cases studied during 1983-1987. The risk factors identified in our study are lack of immunization and administration of intramuscular injections during the pre-paralytic phase. Ensuring early administration of multiple doses of oral polio vaccine to infants and avoiding intramuscular injections in young febrile children are important measures for the control of poliomyelitis--a continuing problem in Southern India. |
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Authors:
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S Mahadevan; S Ananthakrishnan; S Srinivasan; P Nalini; R K Puri; S Badrinath; R S Rao |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of tropical medicine and hygiene Volume: 92 ISSN: 0022-5304 ISO Abbreviation: J Trop Med Hyg Publication Date: 1989 Dec |
Date Detail:
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Created Date: 1990-02-15 Completed Date: 1990-02-15 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0406044 Medline TA: J Trop Med Hyg Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 416-21 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Fawaharlal Institute of Post-Graduate Medical Education and Research, Pondicherry, India. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Child, Preschool Disease Outbreaks* Female Humans Immunization India / epidemiology Infant Male Poliomyelitis / epidemiology*, mortality Poliovirus / isolation & purification Poliovirus Vaccine, Oral / administration & dosage* Risk Factors Seasons Sex Factors |
| Chemical | |
Reg. No./Substance:
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0/Poliovirus Vaccine, Oral |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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