| Polio trial: an early efficient clinical trial. | |
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MedLine Citation:
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PMID: 2189187 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The Salk Vaccine Field Trial was a randomized, placebo-controlled trial designed to test the efficacy of the Salk killed virus vaccine. Although the trial was not without some problems, both in design and analysis, none was important enough to raise serious questions about the results. Thus, the design of the Field Trial was well adapted to the demanding requirements. The trial owes its success in a large part to substantial public involvement. In designing future, large-scale, simple trials, we may still be able to benefit from the lessons of the Polio Vaccine Trial. |
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Authors:
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P Meier |
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Publication Detail:
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Type: Clinical Trial; Historical Article; Journal Article; Multicenter Study; Randomized Controlled Trial |
Journal Detail:
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Title: Statistics in medicine Volume: 9 ISSN: 0277-6715 ISO Abbreviation: Stat Med Publication Date: 1990 Jan-Feb |
Date Detail:
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Created Date: 1990-06-29 Completed Date: 1990-06-29 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8215016 Medline TA: Stat Med Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 13-6 Citation Subset: IM; Q |
Affiliation:
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Department of Statistics, University of Chicago, IL 60637. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Child History, 20th Century Humans Multicenter Studies as Topic Poliovirus Vaccine, Inactivated / history* Randomized Controlled Trials as Topic / history* United States |
| Chemical | |
Reg. No./Substance:
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0/Poliovirus Vaccine, Inactivated |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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