Document Detail

Policy statement on iron deficiency in pre-school-aged children.
MedLine Citation:
PMID:  17635678     Owner:  NLM     Status:  MEDLINE    
AIM: We aimed to develop policy in relation to three areas: (i) the diagnosis of iron deficiency; (ii) maternal-infant issues and the prevention of iron deficiency; and (iii) the treatment of iron deficiency. METHODS: Within each of these topic areas we completed a literature review and developed recommendations to help direct activities of the Royal Australasian College of Physicians, update paediatricians and guide clinical practice. RESULTS: Iron deficiency can be defined using cut-off values for laboratory measures of iron status or, if an intercurrent infection is not present, by demonstrating a response to a therapeutic trial of iron. The appropriate measures of iron status vary depending upon the presence of intercurrent infection. Full-term babies are born with iron stores sufficient to meet their needs to age 4-6 months but premature infants are not. After age 6 months infants are dependent upon dietary iron from complementary foods even with continued breastfeeding. Infants <33 weeks gestation or <1800 g birthweight should receive iron from 4 weeks of age. In most settings recommended treatment of iron deficiency is with oral ferrous sulphate as a single or twice daily dose of between 3 and 6 mg/kg/day. CONCLUSIONS: Iron deficiency is prevalent and an important determinant of child health. Precise and accurate diagnosis remains challenging. Iron supplementation is required for premature and low-birthweight infants. Oral iron salts remain the recommended treatment of choice in most instances.
Cameron C Grant; Clare R Wall; David Brewster; Ross Nicholson; John Whitehall; Leanne Super; Lydia Pitcher
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of paediatrics and child health     Volume:  43     ISSN:  1034-4810     ISO Abbreviation:  J Paediatr Child Health     Publication Date:    2007 Jul-Aug
Date Detail:
Created Date:  2007-07-19     Completed Date:  2008-01-17     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9005421     Medline TA:  J Paediatr Child Health     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  513-21     Citation Subset:  IM    
Department of Paediatrics, University of Auckland, Auckland, New Zealand.
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MeSH Terms
Anemia, Iron-Deficiency* / blood,  diet therapy,  prevention & control
Child, Preschool
Ferrous Compounds / therapeutic use
Health Policy*
Infant Nutritional Physiological Phenomena
Infant, Newborn
Iron, Dietary / administration & dosage
New Zealand
Practice Guidelines as Topic
Prenatal Care
Reg. No./Substance:
0/Ferrous Compounds; 0/Iron, Dietary; 7720-78-7/ferrous sulfate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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