Document Detail

PoleStriding exercise and vitamin E for management of peripheral vascular disease.
MedLine Citation:
PMID:  12618567     Owner:  NLM     Status:  MEDLINE    
PURPOSE: The purpose of this investigation was to evaluate the efficacy of PoleStriding exercise (a form of walking that uses muscles of the upper and lower body in a continuous movement similar to cross-country skiing) and vitamin E (alpha-tocopherol) to improve walking ability and perceived quality of life (QOL) of patients with claudication pain secondary to peripheral arterial disease (PAD). METHODS: Fifty-two subjects were randomized into four groups: PoleStriding with vitamin E (N = 13), PoleStriding with placebo (N= 14), vitamin E without exercise (N= 13), and placebo without exercise (N = 12). The dose of vitamin E was 400 IU daily. Only the PoleStriding with vitamin E and PoleStriding with placebo groups received PoleStriding instruction and training. Assignment to vitamin E or placebo was double blind. Subjects trained three times weekly for 30-45 min (rest time excluded). Individuals in vitamin E and placebo groups came to the laboratory biweekly for ankle blood-pressure measurements. RESULTS: Results of this randomized clinical trial provide strong evidence that PoleStriding significantly (P< 0.001) improved exercise tolerance on the constant work-rate and incremental treadmill tests. Ratings of perceived claudication pain were significantly less after the PoleStriding training program (P= 0.02). In contrast, vitamin E did not have a statistically significant effect on the subjects' ratings of perceived leg pain (P= 0.35) or treadmill walking duration ( P= 0.36). Perceived distance and walking speed (Walking Impairment Questionnaire) and perceived physical function (Rand Short Form-36) improved in the PoleStriding trained group only (P< 0.001, 0.022 and 0.003, respectively). CONCLUSION: PoleStriding effectively improved the exercise tolerance and perceived QOL of patients with PAD. Little additional benefit to exercise capacity was realized from vitamin E supplementation.
Eileen G Collins; W Edwin Langbein; Cynthia Orebaugh; Christine Bammert; Karla Hanson; Domenic Reda; Lonnie C Edwards; Fred N Littooy
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Medicine and science in sports and exercise     Volume:  35     ISSN:  0195-9131     ISO Abbreviation:  Med Sci Sports Exerc     Publication Date:  2003 Mar 
Date Detail:
Created Date:  2003-03-05     Completed Date:  2003-07-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8005433     Medline TA:  Med Sci Sports Exerc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  384-93     Citation Subset:  IM; S    
Research and Development Service, College of Nursing at University of Illinois Chicago, Chicago, IL 60141, USA.
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MeSH Terms
Activities of Daily Living / psychology
Disease Management
Double-Blind Method
Exercise Test
Exercise Therapy*
Exercise Tolerance / drug effects,  physiology
Follow-Up Studies
Intermittent Claudication / physiopathology,  therapy
Leg / blood supply*,  pathology*
Middle Aged
Oxygen Consumption / drug effects,  physiology
Patient Compliance
Peripheral Vascular Diseases / physiopathology*,  therapy*
Physical Endurance / drug effects,  physiology
Prospective Studies
Quality of Life / psychology
Randomized Controlled Trials as Topic
Regional Blood Flow / drug effects,  physiology
Time Factors
Treatment Outcome
Vitamin E / therapeutic use*
Walking / physiology
Reg. No./Substance:
1406-18-4/Vitamin E

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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