| Polarographic reduction and carcinogenic index tg alpha of 5-aza nucleosides possessing antileukemic activity. | |
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MedLine Citation:
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PMID: 7505887 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Polarographic behavior of arabinosyl-5-azacytosine (ara-AC) and 5-azacytidine in anhydrous dimethylformamide and in Britton Robinson buffer is described. 5-Azacytidine and ara-AC underwent two-electron reduction under the polarographic conditions used. Carcinogenic index tg alpha estimated in the presence of alpha-lipoic acid was 0.295 for 5-azacytidine and 0.275 for ara-AC. |
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Authors:
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A Vachálková; L Novotný; A Pískala |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Neoplasma Volume: 40 ISSN: 0028-2685 ISO Abbreviation: Neoplasma Publication Date: 1993 |
Date Detail:
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Created Date: 1994-02-01 Completed Date: 1994-02-01 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0377266 Medline TA: Neoplasma Country: CZECH REPUBLIC |
Other Details:
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Languages: eng Pagination: 289-92 Citation Subset: IM |
Affiliation:
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Department of Experimental Therapy, Slovak Academy of Sciences, Bratislava. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antineoplastic Agents
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chemistry* Azacitidine / chemistry*, toxicity* Carcinogens / chemistry, toxicity* Cytarabine / chemistry Cytidine / chemistry Molecular Structure Oxidation-Reduction Polarography Structure-Activity Relationship |
| Chemical | |
Reg. No./Substance:
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0/Antineoplastic Agents; 0/Carcinogens; 147-94-4/Cytarabine; 320-67-2/Azacitidine; 65-46-3/Cytidine; 65886-71-7/fazarabine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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