Document Detail

Poisoning as a result of barium styphnate explosion.
MedLine Citation:
PMID:  11920972     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Acute barium poisoning is most often the result of accidental or suicidal ingestion of the rodenticide, barium carbonate. We describe a trauma patient whose condition was complicated by severe acute barium toxicity from an explosion of the propellant, barium styphnate. In addition to critical injuries, the patient manifested classic signs of barium toxicity including repeated profound hypokalemia, cardiac arrhythmias, respiratory failure, prolonged gastrointestinal dysfunction, paralysis, myoclonus, hypertension, and profound lactic acidosis. METHODS: The patient required lidocaine for ventricular bigeminy, massive infusions of potassium, prolonged ventilatory support, and parenteral nutrition to manage the effects of barium toxicity. RESULTS: He is the first reported case to demonstrate recurrent profound hypokalemia as an effect of blood transfusions. CONCLUSIONS: Considering the paucity of information concerning management of this life-threatening problem, the pathophysiology of barium toxicity, including the transfusion related hypokalemia, and its management is reviewed.
Ira A Jacobs; Joseph Taddeo; Kathleen Kelly; Carl Valenziano
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of industrial medicine     Volume:  41     ISSN:  0271-3586     ISO Abbreviation:  Am. J. Ind. Med.     Publication Date:  2002 Apr 
Date Detail:
Created Date:  2002-03-28     Completed Date:  2002-05-20     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8101110     Medline TA:  Am J Ind Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  285-8     Citation Subset:  IM    
Copyright Information:
Copyright 2002 Wiley-Liss, Inc.
Department of Surgery, Morristown Memorial Hospital, Morristown, New Jersey, USA.
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MeSH Terms
Accidents, Occupational
Arrhythmias, Cardiac / chemically induced
Barium / poisoning*
Barium Compounds / administration & dosage
Blood Transfusion / adverse effects
Hypokalemia / chemically induced
Middle Aged
Poisoning / therapy
Reg. No./Substance:
0/Barium Compounds; 0/barium styphnate; 7440-39-3/Barium

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