| Pneumonitis related to docetaxel: case report and review of the literature. | |
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MedLine Citation:
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PMID: 19567400 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Taxotere has recently been making a noticeable impact on breast, gastric, ovarian, prostate and non-small cell lung cancers. Its side effects include dyspnea, pruritus, skin rashes, fever and hypotension. The patient presented the less common, however potentially fatal, toxicity of pneumonitis. He initially presented with a flu-like illness and hypoxia that was unresponsive to antibiotic treatment and actually progressed. He presented 14 days after his second dose of taxotere, although in retrospect noted symptoms several days prior. Although some patients described in the literature have progressed to respiratory failure requiring mechanical ventilation, this patient responded to steroid treatment and withdrawal of taxotere. |
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Authors:
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Susan Alsamarai; Andriani G Charpidou; Richard A Matthay; Daniel Confeld; Kostas N Syrigos; Muhammad W Saif |
Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: In vivo (Athens, Greece) Volume: 23 ISSN: 0258-851X ISO Abbreviation: In Vivo Publication Date: 2009 Jul-Aug |
Date Detail:
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Created Date: 2009-07-01 Completed Date: 2009-09-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8806809 Medline TA: In Vivo Country: Greece |
Other Details:
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Languages: eng Pagination: 635-7 Citation Subset: IM |
Affiliation:
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Department of Clinical Oncology, Yale Univeristy School of Medicine, New Haven, CT, U.S.A. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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drug therapy* Aged Antineoplastic Agents / adverse effects* Esophageal Neoplasms / drug therapy* Humans Male Pneumonia / chemically induced*, radiography Taxoids / adverse effects* |
| Chemical | |
Reg. No./Substance:
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0/Antineoplastic Agents; 0/Taxoids; 114977-28-5/docetaxel |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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