Document Detail

Pneumonitis associated with natural and recombinant interferon alfa therapy for chronic hepatitis C.
MedLine Citation:
PMID:  8131569     Owner:  NLM     Status:  MEDLINE    
We report three cases of chronic hepatitis C (HC) with pneumonitis, suspected to be caused by natural and recombinant interferon (INF) alfa treatments. The patients were administered INF through intramuscular injection. All three patients developed acute respiratory failure (PaO2 < or = 60 mm Hg) with bilateral lung infiltration. One of the patient's condition improved after the cessation of INF treatment, without any other therapy. The other two patients were administered corticosteroids, and one patient's condition improved, while in the other patient the pneumonitis persisted, even after a high dose of corticosteroids. To our knowledge, these three cases are the first report of pneumonitis associated with INF alfa in patients with chronic HC.
K Chin; C Tabata; N Sataka; S Nagai; F Moriyasu; K Kuno
Related Documents :
18181739 - Respiratory syncytial virus infection in patients with hematological diseases: single-c...
11256279 - Evaluation of high-speed treadmill videoendoscopy for diagnosis of upper respiratory tr...
707889 - Excessive polycythemia of high altitude: role of ventilatory drive and lung disease.
20661679 - Microcirculatory abnormalities in patients with severe influenza a (h1n1) infection.
20436689 - Role of noninvasive ventilation in weaning from mechanical ventilation in patients of c...
24814979 - Relationship between expression of human gingival beta-defensins and levels of periodon...
17188339 - Variation and importance of aspirin resistance in patients with known cardiovascular di...
1787499 - Lymphoma developing in a patient with rheumatoid arthritis taking low dose weekly metho...
11162759 - Physically traumatic events in patients with epilepsy compared with non-epileptic subje...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Chest     Volume:  105     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1994 Mar 
Date Detail:
Created Date:  1994-04-15     Completed Date:  1994-04-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  939-41     Citation Subset:  AIM; IM    
Department of Clinical Physiology, Kyoto University, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Hepatitis C / therapy*
Hepatitis, Chronic / therapy*
Injections, Intramuscular
Interferon Type I, Recombinant / administration & dosage,  adverse effects*,  therapeutic use
Interferon-alpha / administration & dosage,  adverse effects*,  therapeutic use
Middle Aged
Pneumonia / etiology*,  radiography
Respiratory Insufficiency / etiology
Reg. No./Substance:
0/Interferon Type I, Recombinant; 0/Interferon-alpha

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Concertina-like phenomenon in ventricular preexcitation due to spontaneous atrioventricular nodal We...
Next Document:  Malignant thymoma. A complicated triad of SVC syndrome, cardiac tamponade, and DIC.