Document Detail

Pneumonia in the surgical intensive care unit: factors determining successful outcome.
MedLine Citation:
PMID:  8135314     Owner:  NLM     Status:  MEDLINE    
A review of 85 consecutive patients who acquired pneumonia in a surgical intensive care unit revealed several parameters associated with successful treatment. Fifty-five patients (65%) recovered after a single course of antimicrobial therapy. Statistical analysis demonstrated significant differences between those treated successfully and those whose therapy failed during the duration of intubation (7.2 +/- 1.5 days versus 29.3 +/- 4.3 days), duration of ventilation (6.7 +/- 1.4 days versus 14.8 +/- 3.2 days), and the alveolar-arterial oxygen gradient on the day of diagnosis (215 +/- 23 mm Hg versus 343 +/- 33 mm Hg, all p < 0.01). Multiple antimicrobial resistance was uncommon in bacteria isolated on initial culture but occurred in two thirds of patients with treatment failures. Pneumonia due to Pseudomonas aeruginosa and Staphylococcus aureus were associated with the highest rate of treatment failure, which were 56% and 45%, respectively.
M A Malangoni; R Crafton; F C Mocek
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of surgery     Volume:  167     ISSN:  0002-9610     ISO Abbreviation:  Am. J. Surg.     Publication Date:  1994 Feb 
Date Detail:
Created Date:  1994-04-21     Completed Date:  1994-04-21     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370473     Medline TA:  Am J Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  250-5     Citation Subset:  AIM; IM    
Department of Surgery, University of Louisville School of Medicine, Kentucky.
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MeSH Terms
Aged, 80 and over
Cross Infection / microbiology,  physiopathology,  therapy*
Intensive Care Units
Middle Aged
Pneumonia / microbiology,  physiopathology,  therapy*
Postoperative Complications / microbiology,  physiopathology,  therapy*
Pulmonary Gas Exchange / physiology*
Retrospective Studies
Risk Factors
Statistics as Topic
Treatment Failure
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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