Document Detail

Pneumomediastinum and subcutaneous emphysema secondary to amyopathic dermatomyositis with cryptogenic organizing pneumonia in invasive breast cancer: a case report and review of literature.
MedLine Citation:
PMID:  19093118     Owner:  NLM     Status:  MEDLINE    
Amyopathic dermatomyositis (ADM) is recognized as a variant phenotype of dermatomyositis and characterized by typical skin manifestations without evidence of muscular inflammation. While interstitial lung disease (ILD) is occasionally found as one of the lung manifestations in ADM patients, the development of a pneumomediastinum and/or subcutaneous emphysema in this disease entity is one of the extremely rare pulmonary complications. These latter complicated pulmonary manifestations have been usually reported in idiopathic ADM with ILD without any other associated medical conditions. We report a case presented with the spontaneous pneumomediastinum and subcutaneous emphysema in both ADM and cryptogenic organizing pneumonia during adjuvant chemotherapy based on cyclophosphamide for breast cancer.
Sung Hwan Park; Yoon-Seup Kum; Kyung-Chan Kim; Jung-Yoon Choe; Sung-Hoon Park; Seong-Kyu Kim
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2008-12-18
Journal Detail:
Title:  Rheumatology international     Volume:  29     ISSN:  1437-160X     ISO Abbreviation:  Rheumatol. Int.     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-07-29     Completed Date:  2009-11-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8206885     Medline TA:  Rheumatol Int     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1231-5     Citation Subset:  IM    
Department of General Surgery, Catholic University of Daegu School of Medicine, Daegu, South Korea.
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MeSH Terms
Breast Neoplasms / complications*,  drug therapy,  pathology*
Chemotherapy, Adjuvant / methods
Cryptogenic Organizing Pneumonia / diagnosis*
Cyclophosphamide / therapeutic use
Dermatomyositis / complications*,  diagnosis
Follow-Up Studies
Immunosuppressive Agents / therapeutic use
Lung / radiography
Mediastinal Emphysema / complications*,  diagnosis,  radiography
Middle Aged
Neoplasm Invasiveness
Subcutaneous Emphysema / etiology,  radiography*
Time Factors
Treatment Outcome
Reg. No./Substance:
0/Immunosuppressive Agents; 50-18-0/Cyclophosphamide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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