Document Detail


Pneumocystis jirovecii pneumonia in a baby with hyper-IgE syndrome.
MedLine Citation:
PMID:  19308447     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 4-month-old baby with a family history of hyper-IgE syndrome acquired Pneumocystis jirovecii pneumonia. The patient's hyper-IgE syndrome score was low, but a genetic study yielded a STAT3 mutation. P. jirovecii pneumonia can be added to the infections associated with hyper-IgE syndrome. In some cases, it may be the presenting manifestation of this immunodeficiency.
Authors:
Ben Zion Garty; Adit Ben-Baruch; Asaf Rolinsky; Cristina Woellner; Bodo Grimbacher; Nufar Marcus
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-03-24
Journal Detail:
Title:  European journal of pediatrics     Volume:  169     ISSN:  1432-1076     ISO Abbreviation:  Eur. J. Pediatr.     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2009-11-12     Completed Date:  2010-02-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7603873     Medline TA:  Eur J Pediatr     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  35-7     Citation Subset:  IM    
Affiliation:
Department of Pediatrics B, Schneider Children's Medical Center of Israel, Petah Tiqwa 49202, Israel. gartyb@clalit.org.il
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MeSH Terms
Descriptor/Qualifier:
Antibodies, Bacterial / analysis
Bronchoalveolar Lavage Fluid / microbiology
DNA, Bacterial / analysis
Diagnosis, Differential
Humans
Immunoglobulin E / blood*
Infant
Job's Syndrome / blood,  complications*,  immunology
Male
Pneumocystis jirovecii / genetics,  immunology,  isolation & purification*
Pneumonia, Pneumocystis / diagnosis,  etiology*,  microbiology
Radiography, Thoracic
T-Lymphocytes, Regulatory / immunology
Chemical
Reg. No./Substance:
0/Antibodies, Bacterial; 0/DNA, Bacterial; 37341-29-0/Immunoglobulin E

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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