| Pneumococcal vaccination among adults with chronic respiratory diseases: a historical overview. | |
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MedLine Citation:
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PMID: 22309670 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Streptococcus pneumoniae, the most common cause of community-acquired pneumonia, remains a major cause of morbidity and mortality worldwide. The presence of chronic respiratory illness is a major risk factor for pneumonia, and smoking (the most common cause of chronic obstructive pulmonary disease) is also an important risk factor for pneumonia and invasive pneumococcal disease. There are currently three established approaches to antipneumococcal vaccination: capsular polysaccharide pneumococcal vaccines (recommended for adults and some children at risk), protein-polysaccharide conjugate pneumococcal vaccines (classically recommended for infants and young children and currently under evaluation for adults aged 50 years or older for the prevention of invasive disease) and experimental protein-based pneumococcal vaccines (under investigation in animal models). Although patients with chronic respiratory diseases are commonly described as an at-risk population for pneumococcal infections, studies on pneumococcal vaccination efficacy in such patients are very limited and vaccination effectiveness remains controversial. This paper reviews available data on the efficacy and effectiveness of polysaccharide pneumococcal vaccination among adults with chronic respiratory diseases. |
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Authors:
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Angel Vila-Corcoles; Olga Ochoa-Gondar |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Expert review of vaccines Volume: 11 ISSN: 1744-8395 ISO Abbreviation: Expert Rev Vaccines Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-02-07 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101155475 Medline TA: Expert Rev Vaccines Country: England |
Other Details:
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Languages: eng Pagination: 221-36 Citation Subset: IM |
Affiliation:
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Primary Care Service of Tarragona, EPIVAC Study Group, Institut Catala de la Salut, Prat de la Riba 39, 43001, Tarragona, Spain. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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