Document Detail

Pneumococcal polysaccharide capsular antigens in chronic secretory otitis media.
MedLine Citation:
PMID:  6363320     Owner:  NLM     Status:  MEDLINE    
In a series of 163 ears with chronic, mucoid effusion, free or immune complex bound pneumococcal capsular polysaccharide antigens were demonstrated with Omniserum and counterimmunoelectrophoresis (CIEP) in 37 ears (23%). In crushed adenoid tissue this figure was 39% (42/107). Using type- or group-specific sera pneumococcus type 6 was found to be most frequent (56%) followed by type 19 (17%). A similar trend was also seen in adenoid suspensions. The results suggest that development of secretory otitis media is much more linked with the pneumococcal serotypes than has been thought hitherto, and that type 6 occurs significantly more often bound in immune complexes than any other subtype.
T Palva; T Lehtinen; H Virtanen
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of pediatric otorhinolaryngology     Volume:  6     ISSN:  0165-5876     ISO Abbreviation:  Int. J. Pediatr. Otorhinolaryngol.     Publication Date:  1983 Nov 
Date Detail:
Created Date:  1984-03-20     Completed Date:  1984-03-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8003603     Medline TA:  Int J Pediatr Otorhinolaryngol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  145-9     Citation Subset:  IM    
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MeSH Terms
Adenoids / immunology,  pathology
Antigen-Antibody Complex / immunology
Bacteriological Techniques
Chronic Disease
Otitis Media / immunology*
Otitis Media with Effusion / immunology*
Polysaccharides, Bacterial / immunology*
Streptococcus pneumoniae / immunology*
Reg. No./Substance:
0/Antigen-Antibody Complex; 0/Polysaccharides, Bacterial

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