Document Detail


Pneumococcal meningitis in community is frequent after craniocerebral trauma and in alcohol abusers.
MedLine Citation:
PMID:  18030267     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Aim of this short communication was to assess risk factors and outcome of community acquired pneumococcal meningitis and compare it to all cases of community acquired meningitis. Univariate analysis was used for comparison of 68 pneumococcal to 201 CBM within a Slovak nationwide database of CBM. Significant risk factors for pneumococcal meningitis were previous craniocerebral trauma within 7 days (39.7% vs. 14.9%, p=0.00002), splenectomy (10.3% vs. 3.5%, p=0.03) and alcohol abuse (36.8% vs. 15.4%, p=0.0001). Concerning outcome, mortality was similar (8,8% and 12,4%, NS), proportion of those with neurologic sequellae after CBM due to Str. pneumoniae was insignificantly higher (20.6% vs. 15.4%, NS) in comparison to all CBM. All but 2 strains Str. pneumoniae were susceptible to penicillin and macrolides (3.3% resistance).
Authors:
J Benca; A Lesnakova; K Holeckova; A Ondrusova; O Wiczmandyova; V Sladecko; F Hvizdak; M Bartkovjak; S Seckova; M Taziarova; M Huttova; M Bielova; R Luzica; M Karvaj; M Kovac; F Bauer; I Sabo; V Svabova; L Findova; P Bukovinova; A Shahum
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Neuro endocrinology letters     Volume:  28 Suppl 3     ISSN:  0172-780X     ISO Abbreviation:  Neuro Endocrinol. Lett.     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2007-12-28     Completed Date:  2008-02-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8008373     Medline TA:  Neuro Endocrinol Lett     Country:  Sweden    
Other Details:
Languages:  eng     Pagination:  16-7     Citation Subset:  IM    
Affiliation:
St. Elizabeth University College, Tropical Projects, Gordim, Nyamlel, Slovakia.
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MeSH Terms
Descriptor/Qualifier:
Alcohol-Related Disorders / complications
Anti-Bacterial Agents / therapeutic use
Community-Acquired Infections / complications,  microbiology,  therapy
Craniocerebral Trauma / complications*
Humans
Macrolides / therapeutic use
Meningitis / complications*,  therapy
Meningitis, Pneumococcal / complications*,  therapy
Outcome Assessment (Health Care)
Penicillins / therapeutic use
Risk Factors
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Macrolides; 0/Penicillins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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