Document Detail


Pneumococcal meningitis following parenteral alimentation in infants.
MedLine Citation:
PMID:  6423799     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Three young infants with protracted diarrhea and malnutrition were successfully treated by means of intravenous nutrition, which included infusions of fat emulsion (Intralipid) and of fresh frozen plasma. Three to five weeks after termination of intravenous feeding, and after full recovery, they developed pneumococcal septicemia and meningitis. One infant died, and postmortem examination showed diffuse deposition of "intravenous fat pigment" in hepatocytes and in reticuloendothelial cells. In the two infants who recovered, follow-up studies did not disclose any primary derangement of immunologic function. We propose that the infused fat may have caused a temporary depression of immunologic defense mechanisms, predisposing these infants to the pneumococcal infection; the delay in onset of the infection might be attributed to a short-lasting protective effect of fresh frozen plasma which was included in the intravenous feeding regimen.
Authors:
M Berant; U Alon
Related Documents :
569439 - Meningitis caused by streptococcus dysgalactiae in a preterm infant.
20064869 - Defining cerebrospinal fluid white blood cell count reference values in neonates and yo...
10541939 - Pasteurella multocida meningitis in infancy - (a lick may be as bad as a bite).
11419499 - Systemic nontyphoidal salmonella infection in normal infants in thailand.
6397449 - Recent advances in management of bacterial meningitis in neonates.
6321189 - The cephalosporin compounds in severe neonatal infection.
9743029 - Pediatric death certification.
25424209 - Effect of diaper cream and wet wipes on skin barrier properties in infants: a prospecti...
8959419 - Repeat fertility and contraceptive implant use among medicaid recipients in colorado.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of pediatric gastroenterology and nutrition     Volume:  3     ISSN:  0277-2116     ISO Abbreviation:  J. Pediatr. Gastroenterol. Nutr.     Publication Date:  1984 Mar 
Date Detail:
Created Date:  1984-05-08     Completed Date:  1984-05-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8211545     Medline TA:  J Pediatr Gastroenterol Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  312-4     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Blood / microbiology
Diarrhea, Infantile / therapy
Fat Emulsions, Intravenous / administration & dosage
Female
Humans
Infant
Male
Meningitis, Pneumococcal / etiology*
Parenteral Nutrition / adverse effects*
Streptococcus pneumoniae / isolation & purification
Chemical
Reg. No./Substance:
0/Fat Emulsions, Intravenous

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Effect of casein versus casein hydrolysate on mucosal adaptation following massive bowel resection i...
Next Document:  Ocular abnormalities in terminal deletion of the long arm of chromosome seven.