| Pneumococcal bacteriology after pneumococcal otitis media with special reference to pneumococcal antigens. | |
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MedLine Citation:
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PMID: 3879247 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Fifty-four ears with evidence of pneumococcus (Pn) in the first acute otitis media (AOM) in 38 infants and with prolongation or recurrence of the MEF during the follow-up were observed for 7-22 months for the presence of Pn by culture or of pneumococcal antigen (Pn-ag) by counterimmunoelectrophoresis or latex agglutination methods in their MEFs. During the first three 1-month observation periods, Pn and/or Pn-ags were detected in 24% to 9% of these ears, always of the initial type/group. Later on new Pn types/groups appeared also. In two of the 9 MEFs persisting for greater than or equal to 3 months, initial Pn-ag, with culturable Pn, was repeatedly found but not for longer than 5 months. Of the 12 ears resulting in secretory otitis media (SOM) only one showed initial Pn-ag (and Pn) in the MEF of SOM. Pneumococcal type/group pattern associated with prolongation or recurrence of infection did not differ from that of initial AOM. In another series of 151 SOM ears in 97 children, Pn-ags were detected in 7 MEFs. Four of them grew Pn, each of the corresponding group. Our studies suggest that the persistence of Pn-ags in the middle ear after AOM is limited and their occurrence in the MEFs of SOM is rare. Thus, the role of the persistence of Pn-ags in prolonged, recurrent or secretory otitis media seems questionable. |
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Authors:
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P Karma; P Sipilä; T Virtanen; J Luotonen; M Sipilä; V M Häivä |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: International journal of pediatric otorhinolaryngology Volume: 10 ISSN: 0165-5876 ISO Abbreviation: Int. J. Pediatr. Otorhinolaryngol. Publication Date: 1985 Nov |
Date Detail:
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Created Date: 1986-04-02 Completed Date: 1986-04-02 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8003603 Medline TA: Int J Pediatr Otorhinolaryngol Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 181-90 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Adolescent Antigens, Bacterial / immunology* Child Child, Preschool Female Follow-Up Studies Haemophilus influenzae / isolation & purification Humans Infant Male Otitis Media with Effusion / immunology*, microbiology Pneumococcal Infections / immunology* Serotyping Streptococcus pneumoniae / immunology*, isolation & purification Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Antigens, Bacterial |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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