Document Detail


Pneumatosis intestinalis after bone marrow transplantation.
MedLine Citation:
PMID:  3287869     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The clinical and pathologic data in 18 patients in whom pneumatosis intestinalis developed after bone marrow transplantation were reviewed to determine the significance of this finding. The colon, predominantly the right side, was involved in 17 of the 18 cases. Pneumatosis intestinalis developed earlier in the 14 symptomatic patients than in the four asymptomatic patients. Symptoms included diarrhea (12 patients), abdominal pain (six patients), rectal bleeding (two patients), and abdominal distension (two patients). Factors contributing to the development of pneumatosis intestinalis included pretransplantation chemotherapy and radiotherapy, steroid therapy, infectious colitis, graft-versus-host disease, and septic shock. Intestinal disease contributed to the deaths of seven patients with pneumatosis intestinalis, necessitated right hemicolectomy in another patient, and resolved with conservative treatment in 10 patients. In summary, bone marrow transplant recipients with pneumatosis intestinalis may follow either a benign or fatal course, depending on the underlying condition of the patient. Clinical correlation is important in determining the significance of this finding.
Authors:
D L Day; N K Ramsay; J G Letourneau
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  AJR. American journal of roentgenology     Volume:  151     ISSN:  0361-803X     ISO Abbreviation:  AJR Am J Roentgenol     Publication Date:  1988 Jul 
Date Detail:
Created Date:  1988-07-08     Completed Date:  1988-07-08     Revised Date:  2008-02-15    
Medline Journal Info:
Nlm Unique ID:  7708173     Medline TA:  AJR Am J Roentgenol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  85-7     Citation Subset:  AIM; IM    
Affiliation:
Department of Radiology, University of Minnesota Hospitals, Minneapolis 55455.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Bone Marrow Transplantation*
Child
Child, Preschool
Female
Humans
Male
Pneumatosis Cystoides Intestinalis / etiology*,  radiography
Postoperative Complications / etiology,  radiography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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