Document Detail


Plugging it in: signaling circuits and the yeast cell cycle.
MedLine Citation:
PMID:  8791423     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Signal transduction pathways provide the means to transmit information and elicit specific responses. Modulation of the cell cycle machinery is one such response. Molecular genetic approaches with budding yeast have been instrumental in elucidating the components of these complex signaling pathways and the inter-relationships among these components. Recent progress has revealed pathways that link extracellular signals with the machinery governing both cell cycle progression and morphogenesis. The nature of the interface between nutritional and checkpoint signals with the cell cycle apparatus is just now emerging.
Authors:
C Wittenberg; S I Reed
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Current opinion in cell biology     Volume:  8     ISSN:  0955-0674     ISO Abbreviation:  Curr. Opin. Cell Biol.     Publication Date:  1996 Apr 
Date Detail:
Created Date:  1996-10-24     Completed Date:  1996-10-24     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8913428     Medline TA:  Curr Opin Cell Biol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  223-30     Citation Subset:  IM    
Affiliation:
Curt Wittenberg, Department of Molecular Biology, MB-3, The Scripps Research Institute, 10666 N Torrey Pines Road, La Jolla, CA 92037, USA. curtw@scripps.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Cell Cycle / physiology*
Cyclic AMP / metabolism
Fungal Proteins / metabolism
Haploidy
Humans
Pheromones / metabolism
Saccharomyces cerevisiae / cytology,  physiology*
Signal Transduction / physiology*
Grant Support
ID/Acronym/Agency:
GM38328/GM/NIGMS NIH HHS; GM43487/GM/NIGMS NIH HHS; GM46006/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/Fungal Proteins; 0/Pheromones; 60-92-4/Cyclic AMP

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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