| Ploidy determination of Canadida albicans. | |
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MedLine Citation:
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PMID: 391796 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The dimorphic yeast Candida albicans, as a member of the fungi imperfecti, has been assumed to be in the haploid, or imperfect, state. The deoxyribonucleic acid content of this species has been measured by flow microfluorometry, a technique capable of analyzing single cells. These results were compared with flow microfluorometric deoxyribonucleic acid determinations on a series of strains of Saccharomyces cerevisiae of known ploidy (haploid, diploid, triploid, and tetraploid). These ploidy levels were readily distinguished by the flow microfluorometry procedure. By this criterion, C. albicans was found to contain a diploid amount of deoxyribonucleic acid. Ultraviolet radiation survival and chemical mutagenesis experiments support the conclusion that both clinically isolated and laboratory strains of C. albicans are diploid. |
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Authors:
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A F Olaiya; S J Sogin |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of bacteriology Volume: 140 ISSN: 0021-9193 ISO Abbreviation: J. Bacteriol. Publication Date: 1979 Dec |
Date Detail:
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Created Date: 1980-03-27 Completed Date: 1980-03-27 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 2985120R Medline TA: J Bacteriol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1043-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Candida albicans
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analysis,
genetics* DNA, Fungal / analysis* Diploidy Fluorometry / methods Ploidies* Saccharomyces cerevisiae / analysis, genetics Species Specificity |
| Chemical | |
Reg. No./Substance:
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0/DNA, Fungal |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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