Document Detail

Pleuropulmonary disease due to pergolide use for restless legs syndrome.
MedLine Citation:
PMID:  11451859     Owner:  NLM     Status:  MEDLINE    
Pergolide is an ergot-derived dopamine agonist used in Parkinson's disease and, increasingly, in restless legs syndrome. We report a patient with a 2.5-year history of weight loss, pleuropulmonary fibrosis, and exudative pleural effusion that developed insidiously while taking this medication. The extensive and invasive workup that preceded the diagnosis highlights the difficulty in attributing such a process to a drug reaction. This is the second report of such a reaction to pergolide, which is one of the increasing number of ergot-derived compounds in common clinical use.
S K Danoff; M E Grasso; P B Terry; J A Flynn
Related Documents :
2116429 - The multiple organ failure syndrome.
11442909 - Atrial septal aneurysm and dilated sinus of valsalva in a patient with wolff-parkinson-...
10355929 - Coexisting preexcitation syndrome and intermittent heart block presenting as neonatal s...
19482959 - Caring for the student with wolff-parkinson-white syndrome.
6845079 - The restless legs syndrome (ekbom's syndrome).
11451859 - Pleuropulmonary disease due to pergolide use for restless legs syndrome.
24559749 - Sonoelastography for the evaluation of an axillary schwannoma in a case of quadrilatera...
23514029 - Clinical presentation, aetiology and prognosis of orbital apex syndrome.
15034699 - Aneurysmal sub-arachnoid haemorrhage in patients with noonan syndrome: a report of two ...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Chest     Volume:  120     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  2001 Jul 
Date Detail:
Created Date:  2001-07-13     Completed Date:  2001-08-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  United States    
Other Details:
Languages:  eng     Pagination:  313-6     Citation Subset:  AIM; IM    
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Dopamine Agonists / adverse effects*,  therapeutic use
Pergolide / adverse effects*,  therapeutic use
Pleural Diseases / chemically induced*,  diagnosis
Pleural Effusion / chemically induced
Pulmonary Fibrosis / chemically induced*,  diagnosis
Restless Legs Syndrome / drug therapy*
Reg. No./Substance:
0/Dopamine Agonists; 66104-22-1/Pergolide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Spontaneous hemomediastinum complicating steroid-induced mediastinal lipomatosis.
Next Document:  Treatment of a solitary pulmonary sarcoidosis mass by CT-guided direct intralesional injection of co...