Document Detail

Pleuroparenchymal Fibroelastosis: Its Pathological Characteristics.
MedLine Citation:
PMID:  24634642     Owner:  NLM     Status:  Publisher    
Pleuroparenchymal fibroelastosis (PPFE) is a distinct pattern of pulmonary fibrosis which often runs a rapidly progressive course with a poor prognosis, and it is likely to be introduced as a separate entity in the new classification scheme of idiopathic interstitial pneumonias. It is characterised by pleural fibrosis and subpleural fibroelastosis, with an upper lobe predominance. In addition to cases following lung and bone marrow transplantation, familial and idiopathic cases have been described. The literature on PPFE is fragmented, however, and primarily consists of small case series, lacking a uniform methodology of clinical, radiological and histopathological description. In this review article, most previously published reports of PPFE in the English-language literature will be discussed and the salient clinical and histopathological data analysed to arrive at a working definition of PPFE in daily histopathological practice, and to aid the generation of a unifying hypothesis regarding its potential aetiologies and pathogenesis.
Jan H von der Thüsen
Publication Detail:
Journal Detail:
Title:  Current respiratory medicine reviews     Volume:  9     ISSN:  1573-398X     ISO Abbreviation:  Curr Respir Med Rev     Publication Date:  2013 Aug 
Date Detail:
Created Date:  2014-3-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101240300     Medline TA:  Curr Respir Med Rev     Country:  -    
Other Details:
Languages:  ENG     Pagination:  238-247     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Feasibility of a computerized intervention for offenders with substance use disorders: a research no...
Next Document:  Fabrication and Characterization of Thermoresponsive Films Deposited by an RF Plasma Reactor.