Document Detail


Pleuran (β-Glucan from Pleurotus ostreatus ): An Effective Nutritional Supplement against Upper Respiratory Tract Infections?.
MedLine Citation:
PMID:  23075555     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Prolonged and high-intensity exercise affects immune function and leads to an increased risk of upper respiratory tract infections (URTIs) in endurance athletes. The increased incidence of URTI symptoms may negatively affect athletic performance. Various nutritional supplements have been tested in the last decade for their ability to prevent developing of URTIs or reduce their incidence. One of the most promising nutritional supplements is β-glucan, a well-known immunomodulator with positive effects on functioning of immunocompetent cells. However, β-glucans are a diverse group of molecules that vary in macromolecular structure, solubility, viscosity, molecular weight and biological activity. This fact is supported by results from recent human clinical studies where β-glucans of different origin and properties differed in ability to prevent or reduce incidence of URTIs in athletes. It has been found that pleuran, a unique insoluble β-glucan isolated from mushroom Pleurotus ostreatus, significantly reduced the incidence of URTI symptoms in athletes. In addition, it was able to increase the number of circulating natural killer cells and to prevent reduction of natural killer cell activity. Contrarily, soluble oat β-glucan supplementation did not alter URTI incidence in endurance athletes. This difference suggests that the immunomodulatory capacity of β-glucans is strongly dependent on solubility and structural factors such as backbone structure and degree of branching. This review refers to using pleuran as a natural supplement that is able to protect endurance athletes against development of URTI.
Authors:
Juraj Majtan
Related Documents :
24579435 - The prognostic effect of different types of cardiac rehabilitation in patients with cor...
10502075 - Plasma hypoxanthine and ammonia in humans during prolonged exercise.
8587455 - Plasma endothelin-1 levels after exercise in patients with congenital heart disease.
21161265 - Effect of resistance training during hemodialysis on circulating cytokines: a randomize...
7263435 - Decreased vascular sensitivity to norepinephrine following exercise training.
19842545 - Illuminating the black box: investigating prefrontal cortical hemodynamics during exerc...
Publication Detail:
Type:  Journal Article     Date:  2012-10-15
Journal Detail:
Title:  Medicine and sport science     Volume:  59     ISSN:  1662-2812     ISO Abbreviation:  Med Sport Sci     Publication Date:  2013  
Date Detail:
Created Date:  2012-10-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8402440     Medline TA:  Med Sport Sci     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  57-61     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 S. Karger AG, Basel.
Affiliation:
Institute of Zoology, Slovak Academy of Sciences, and Department of Microbiology, Faculty of Medicine, Slovak Medical University, Bratislava, Slovakia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Exercise, intestinal barrier dysfunction and probiotic supplementation.
Next Document:  Bovine colostrum and immune function after exercise.