Document Detail

Pleural effusions occurring with right heart failure.
MedLine Citation:
PMID:  21623177     Owner:  NLM     Status:  In-Data-Review    
PURPOSE OF REVIEW: Pleural effusions commonly occur in patients with left heart failure. However, there is increasing evidence that patients with pulmonary hypertension and isolated right heart failure frequently have pleural effusions.
RECENT FINDINGS: Three recent studies have evaluated the incidence of pleural effusions without an alternate explanation in patients with idiopathic/familial pulmonary arterial hypertension (14%), pulmonary arterial hypertension associated with connective tissue diseases (33%), and portopulmonary hypertension (30%). The majority of patients in all three studies with pleural effusions without an alternate explanation were found to have isolated right heart failure. In these studies, mean right atrial pressures and death during follow-up were significantly higher in patients with pleural effusions and isolated right heart failure compared to patients with no pleural effusions.
SUMMARY: Pleural effusions without an alternate explanation occur commonly in at least three subtypes of pulmonary arterial hypertension. The majority of patients with pleural effusions also have isolated right heart failure that is thought to be responsible for the development of the effusions. Patients presenting with pulmonary hypertension should be evaluated for pleural effusions, and if present, should receive a work-up for right heart failure.
Anupama G Brixey; Richard W Light
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current opinion in pulmonary medicine     Volume:  17     ISSN:  1531-6971     ISO Abbreviation:  Curr Opin Pulm Med     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-05-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9503765     Medline TA:  Curr Opin Pulm Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  226-31     Citation Subset:  IM    
Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, T-1218 Medical Center North, Nashville, Tennessee, USA.
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