Document Detail

Pleural effusions in hematologic malignancies.
MedLine Citation:
PMID:  15078773     Owner:  NLM     Status:  MEDLINE    
Nearly all hematologic malignancies can occasionally present with or develop pleural effusions during the clinical course of disease. Among the most common disorders are Hodgkin and non-Hodgkin lymphomas, with a frequency of 20 to 30%, especially if mediastinal involvement is present. Acute and chronic leukemias, myelodysplastic syndromes, are rarely accompanied by pleural involvement. Furthermore, 10 to 30% of patients receiving bone marrow transplantation develop pleural effusions. In cases of hematologic pleural effusions, drug toxicity, underlying infectious, secondary malignant or rarely autoimmune causes should be carefully sought. In most cases, the pleural fluid responds to treatment of the primary disease, whereas resistant or relapsing cases may necessitate pleurodesis.
Michael G Alexandrakis; Freda H Passam; Despina S Kyriakou; Demosthenes Bouros
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Chest     Volume:  125     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  2004 Apr 
Date Detail:
Created Date:  2004-04-13     Completed Date:  2004-05-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1546-55     Citation Subset:  AIM; IM    
Department of Hematology, University Hospital of Heraklion, and Medical School, University of Crete, Greece.
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MeSH Terms
Bone Marrow Transplantation
Giant Lymph Node Hyperplasia / complications
Hodgkin Disease / complications
Leukemia / complications*
Leukemia, Hairy Cell / complications
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / complications
Leukemia, Myeloid / complications
Leukemia, Plasma Cell / complications
Lymphoma / complications*
Lymphoma, Non-Hodgkin
Multiple Myeloma / complications
Myelodysplastic Syndromes / complications
Pleural Effusion / etiology*,  therapy
Postoperative Complications
Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications
Radiotherapy / adverse effects
Comment In:
Chest. 2005 May;127(5):1866; author reply 1866-7   [PMID:  15888876 ]

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