Document Detail

Pleural effusion in non-Hodgkin's lymphoma.
MedLine Citation:
PMID:  1582297     Owner:  NLM     Status:  MEDLINE    
Intrathoracic non-Hodgkin's lymphoma (NHL) usually presents with roentgenographic evidence of mediastinal lymph node enlargement, pulmonary masses, pleural effusion, and a clinical picture of a systemic disease with lymphadenopathy. The presentation of NHL with pleural effusion as the major roentgenographic abnormality and no clinical peripheral lymphadenopathy or organomegaly is unusual. During a seven-year period, we encountered 19 patients with NHL in whom pleural effusion was the major roentgenographic and clinical finding. Pleural fluid cytologic results were diagnostic in only two patients. Closed pleural biopsy was positive in three. Eight of 11 patients had diagnostic immunophenotypic lymphocyte cell marker studies. Seven of nine patients had diagnostic thoracoscopy and one thoracotomy. The CT scan identified biopsy sites when pleural fluid and tissue studies were nondiagnostic. Lymphomatous tissue was obtained from the pleura in 17 of the 19 patients supporting the contention that pleural effusion in patients with NHL is usually due to pleural lymphoma rather than obstruction to mediastinal lymphatics.
F Celikoglu; A S Teirstein; D J Krellenstein; J A Strauchen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Chest     Volume:  101     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1992 May 
Date Detail:
Created Date:  1992-06-12     Completed Date:  1992-06-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1357-60     Citation Subset:  AIM; IM    
Mount Sinai Medical Center, New York.
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MeSH Terms
Aged, 80 and over
Lymphoma, Non-Hodgkin / complications*
Middle Aged
Pleura / pathology
Pleural Effusion, Malignant / diagnosis,  etiology*,  radiography
Tomography, X-Ray Computed

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