| Pleiotropic effects of cardilopin (secondary coronary prevention). | |
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MedLine Citation:
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PMID: 15834180 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In order to evaluate some pleiotropic effects of cardilopin (Amlodipine, EGIS Pharmaceuticals) 33 ambulatory patients were examined. During the 2-month study period on the background of cardilopin treatment there were positive changes in some parameters of coronary atherosclerosis. Pleiotropic effects of cardilopin were particularly expressed in restoring of endothelial function and inhibition of platelet aggregation. There was found tendency to reduce the degree of hyperlipoperoxidemia related to oxidative stress. Obtained results of the present trial support the use of cardilopin in all coronary heart disease patients with or without myocardial revascularization and arterial hypertension. |
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Authors:
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S Kapanadze; N Dolidze; Z Bakhutashvili; L Chapidze; E Shengelia |
Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Georgian medical news Volume: - ISSN: 1512-0112 ISO Abbreviation: Georgian Med News Publication Date: 2005 Feb |
Date Detail:
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Created Date: 2005-04-18 Completed Date: 2005-05-26 Revised Date: 2008-05-21 |
Medline Journal Info:
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Nlm Unique ID: 101218222 Medline TA: Georgian Med News Country: Georgia (Republic) |
Other Details:
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Languages: eng Pagination: 46-8 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Amlodipine
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administration & dosage,
pharmacology,
therapeutic use* Blood Pressure / drug effects Blood Pressure Monitors Calcium Channel Blockers / administration & dosage, pharmacology, therapeutic use* Coronary Disease / blood, drug therapy*, metabolism, physiopathology Endothelium, Vascular / physiology Heart Rate Humans Lipid Peroxides / blood Nitric Oxide / blood Oxidative Stress Platelet Aggregation / drug effects Time Factors Vasodilator Agents / administration & dosage, pharmacology, therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Calcium Channel Blockers; 0/Lipid Peroxides; 0/Vasodilator Agents; 10102-43-9/Nitric Oxide; 88150-42-9/Amlodipine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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