Document Detail


Play fighting in androgen-insensitive tfm rats: evidence that androgen receptors are necessary for the development of adult playful attack and defense.
MedLine Citation:
PMID:  16489596     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The frequency of playful attack and the style of playful defense, are modifiable by gonadal steroids and change after puberty in male and female rats. The present study examined the play behavior exhibited by testicular feminized mutation (tfm)-affected males, who are insensitive to androgens but can bind estrogens aromatized from androgens, to determine the relative contributions of androgens and estrogens to the age-related changes in play behavior. tfm males did not exhibit a decrease in playful attack with age and were more likely to maintain the use of complete rotations, a juvenile form of playful defense, into adulthood. tfm males did however, show age related changes in the use of partial rotations and upright postures, two other forms of playful defense, that were similar to normal males. These data suggest that the development of play fighting and defense in males is dependent on both androgen- and estrogen-receptor-mediated effects.
Authors:
Evelyn F Field; Ian Q Whishaw; Sergio M Pellis; Neil V Watson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Developmental psychobiology     Volume:  48     ISSN:  0012-1630     ISO Abbreviation:  Dev Psychobiol     Publication Date:  2006 Mar 
Date Detail:
Created Date:  2006-02-23     Completed Date:  2006-10-04     Revised Date:  2010-04-12    
Medline Journal Info:
Nlm Unique ID:  0164074     Medline TA:  Dev Psychobiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  111-20     Citation Subset:  IM    
Copyright Information:
(c) 2006 Wiley Periodicals, Inc. Dev Psyshobiol 48: 111-120, 2006.
Affiliation:
University of Lethbridge, Lethbridge Alberta, Canada. evelyn.field@uleth.ca
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MeSH Terms
Descriptor/Qualifier:
Age Factors
Agonistic Behavior / physiology*
Androgen-Insensitivity Syndrome / genetics,  physiopathology*
Animals
Female
Male
Play and Playthings*
Rats
Rats, Mutant Strains / physiology*
Rats, Sprague-Dawley
Receptors, Androgen / physiology*
Receptors, Estrogen / physiology
Sex Factors
Chemical
Reg. No./Substance:
0/Receptors, Androgen; 0/Receptors, Estrogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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