Document Detail


Platelet to lymphocyte ratio as a prognostic marker in primary percutaneous coronary intervention.
MedLine Citation:
PMID:  25350375     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract We assessed the prognostic value of the platelet to lymphocyte ratio (PLR) in primary percutaneous coronary intervention (pPCI). Patients (n = 440) with acute myocardial infarction (AMI) who underwent pPCI were divided into 2 groups: low PLR (<137) and high PLR (>137). "Thrombolysis In Myocardial Infarction" (TIMI) flow grades and Syntax scores (SXS) were calculated from initial angiograms. In-hospital mortality rate and cardiac adverse events were obtained from medical records. Patients with high PLR had more no-reflow, higher SXS and higher mortality rate (p < 0.001, p < 0.001 and p = 0.008, respectively). In receiver operating characteristic curve analysis, high PLR predicted development of no-reflow (specificity 71% and sensitivity 85%), SXS>22 (specificity 52% and sensitivity 61%) and adverse events (specificity 67% and sensitivity 63%). In multivariate regression analysis, PLR was an independent risk factor for no-reflow, SXS>22 and in-hospital adverse events. In addition to PLR, we present the relationship between mean platelet volume, red cell distribution width and neutrophil to lymphocyte ratio and no-reflow, SXS and in-hospital adverse events.
Authors:
Burak Ayça; Fatih Akin; Omer Celik; Yasin Yüksel; Derya Oztürk; Fatih Tekiner; Sükrü Cetin; Ertuğrul Okuyan; Hakan Dinçkal M
Related Documents :
17134685 - Myocardial angiogenesis after plasmid or adenoviral vegf-a(165) gene transfer in rat my...
6630775 - Short-term exercise has a prolonged effect on scar formation after experimental acute m...
24986835 - Pharmacologic therapy for reducing myocardial infarct size in clinical trials: failed a...
20307515 - Modulation of ppar-gamma by telmisartan protects the heart against myocardial infarctio...
17194025 - Adenosine deaminase in ischemia reperfusion injury in patients with myocardial infarction.
21820865 - Comprehensive assessment of changes in left atrial volumes and function after st-segmen...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-10-28
Journal Detail:
Title:  Platelets     Volume:  -     ISSN:  1369-1635     ISO Abbreviation:  Platelets     Publication Date:  2014 Oct 
Date Detail:
Created Date:  2014-10-28     Completed Date:  -     Revised Date:  2014-10-29    
Medline Journal Info:
Nlm Unique ID:  9208117     Medline TA:  Platelets     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-7     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Independent Relationship between Amyloid Precursor Protein (APP) Dimerization and ?-Secretase Proces...
Next Document:  Equine model for soft-tissue regeneration.