| Platelet storage and transfusions: new concerns associated with an old therapy. | |
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MedLine Citation:
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PMID: 22662018 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Platelet transfusion has long been practiced with rudimentary knowledge about optimal storage conditions and their implications for efficacy and, particularly, safety. Recent concerns about complications such as inflammation, thrombosis and altered recipient immunity have been raised about platelet transfusion. This review will discuss recent important findings that have raised these issues about platelet transfusion associated morbidity, mortality and the possible role of platelet storage in these associations. |
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Authors:
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Julie Sahler; Katie Grimshaw; Sherry L Spinelli; Majed A Refaai; Richard P Phipps; Neil Blumberg |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-7-20 |
Journal Detail:
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Title: Drug discovery today. Disease mechanisms Volume: 8 ISSN: 1740-6765 ISO Abbreviation: - Publication Date: 2011 |
Date Detail:
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Created Date: 2012-6-4 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101235075 Medline TA: Drug Discov Today Dis Mech Country: - |
Other Details:
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Languages: ENG Pagination: e9-e14 Citation Subset: - |
Affiliation:
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Department of Microbiology and Immunology, University of Rochester. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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