Document Detail


Platelet glycoprotein IIb/IIIa receptor blockade therapy for large coronary aneurysms and thrombi in Kawasaki disease.
MedLine Citation:
PMID:  9829884     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 4-month-old girl with Kawasaki disease, large coronary artery aneurysms, and coronary thrombi was treated with standard therapy followed by abciximab, a platelet glycoprotein IIb/IIIa antagonist, in addition to standard heparin and warfarin sodium anticoagulation and low-dose aspirin. She did not develop evidence of ischemia, had no complications from the therapy, and showed resolution of the aneurysms and thrombi after 6 wk of therapy.
Authors:
S P Etheridge; L Y Tani; L L Minich; J R Revenaugh
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Catheterization and cardiovascular diagnosis     Volume:  45     ISSN:  0098-6569     ISO Abbreviation:  Cathet Cardiovasc Diagn     Publication Date:  1998 Nov 
Date Detail:
Created Date:  1999-01-20     Completed Date:  1999-01-20     Revised Date:  2013-05-24    
Medline Journal Info:
Nlm Unique ID:  7508512     Medline TA:  Cathet Cardiovasc Diagn     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  264-8     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, University of Utah and Primary Children's Medical Center, Salt Lake City 84113, USA. pcs ether@ihc.com
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MeSH Terms
Descriptor/Qualifier:
Antibodies, Monoclonal / therapeutic use
Anticoagulants / therapeutic use
Aspirin / therapeutic use
Cardiac Catheterization
Coronary Aneurysm / complications,  diagnosis,  drug therapy*
Coronary Angiography
Coronary Thrombosis / complications,  diagnosis,  drug therapy*
Drug Therapy, Combination
Echocardiography
Female
Follow-Up Studies
Humans
Immunoglobulin Fab Fragments / therapeutic use
Immunoglobulins, Intravenous / therapeutic use
Infant
Mucocutaneous Lymph Node Syndrome / blood,  complications*,  diagnosis
Platelet Aggregation Inhibitors / therapeutic use*
Platelet Count
Platelet Glycoprotein GPIIb-IIIa Complex / antagonists & inhibitors*
Chemical
Reg. No./Substance:
0/Antibodies, Monoclonal; 0/Anticoagulants; 0/Immunoglobulin Fab Fragments; 0/Immunoglobulins, Intravenous; 0/Platelet Aggregation Inhibitors; 0/Platelet Glycoprotein GPIIb-IIIa Complex; 50-78-2/Aspirin; X85G7936GV/abciximab

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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