| Platelet MAO in patients with idiopathic pain disorders. | |
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MedLine Citation:
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PMID: 3625195 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Patients with idiopathic pain syndromes have been compared to healthy volunteers and patients with neurogenic pain syndromes as concerns the activity of the enzyme monoamine oxidase (MAO) in thrombocytes. In both patients with idiopathic pain syndromes and in patients with neurogenic pain syndromes an increased frequency of patients with low platelet MAO activity was found. As low platelet MAO activity has been suggested to reflect low central serotoninergic activity the results are in line with findings of reduced concentrations of the serotonin metabolite 5-HIAA in CSF in patients with idiopathic pain syndromes. The results would also give some support for the suggestion that idiopathic pain syndromes might be a variant of depressive disease. |
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Authors:
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B G Almay; L von Knorring; L Oreland |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of neural transmission Volume: 69 ISSN: 0300-9564 ISO Abbreviation: J. Neural Transm. Publication Date: 1987 |
Date Detail:
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Created Date: 1987-10-16 Completed Date: 1987-10-16 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0337042 Medline TA: J Neural Transm Country: AUSTRIA |
Other Details:
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Languages: eng Pagination: 243-53 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Blood Platelets / enzymology* Chronic Disease Female Humans Male Middle Aged Monoamine Oxidase / blood* Pain / enzymology*, etiology |
| Chemical | |
Reg. No./Substance:
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EC 1.4.3.4/Monoamine Oxidase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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