Document Detail

Plateau of adiposity in Australian children diagnosed with Type 1 diabetes: a 20-year study.
MedLine Citation:
PMID:  24495260     Owner:  NLM     Status:  Publisher    
AIMS: To examine temporal trends in anthropometry in children with Type 1 diabetes from Sydney, Australia.
METHODS: We conducted a retrospective study in a total of 1975 children with Type 1 diabetes, aged <16 years, between 1990 and 2009. Trends in height, weight and BMI standard deviation score after initial stabilization were examined by age group (<5 years, 5 to <10 years, 10 to 16 years) and time period of diagnosis (T1: 1990-1994, T2: 1995-1999; T3: 2000-2004 and T4: 2005-2009). Factors associated with BMI standard deviation score (time period, age group, gender and socio-economic status) were examined using multivariable linear regression.
RESULTS: The mean BMI standard deviation score (±sd) increased between T1 and T2 (0.54±1.14 vs 0.81±1.14, P=0.002), but remained steady thereafter (T3: 0.85±1.11, T4: 0.87±1.09; T2 to T4: P=0.40). Similarly, the prevalence of overweight and obesity increased from T1 to T2 (26 to 35%, P=0.01), but was unchanged thereafter (T3: 34%, T4: 34%; T2 to T4: P=0.90). On multivariable regression analysis, a higher BMI standard deviation score was associated with younger age (≥5 years vs <5 years, β=-0.40, 95% CI -0.51 to -0.28, P<0.001), later time period (T2 to T4 vs T1, β=0.30, 95% CI 0.16-0.45, P<0.001) and male gender (β=0.25, 95% CI 0.15-0.34, P<0.001).
CONCLUSION: The prevalence of overweight and obesity has remained unchanged in children at diagnosis of Type 1 diabetes over 15 years. These findings suggest that higher adiposity alone cannot account for the continued rising incidence of Type 1 diabetes in recent years. This article is protected by copyright. All rights reserved.
S T Islam; A Abraham; K C Donaghue; A K Chan; M Lloyd; S Srinivasan; M E Craig
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-2-3
Journal Detail:
Title:  Diabetic medicine : a journal of the British Diabetic Association     Volume:  -     ISSN:  1464-5491     ISO Abbreviation:  Diabet. Med.     Publication Date:  2014 Feb 
Date Detail:
Created Date:  2014-2-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8500858     Medline TA:  Diabet Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
This article is protected by copyright. All rights reserved.
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